hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00696.1
Complex Portal: CPX-11942
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SATB1 | DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1) | 5 | UniProt NCBI |
| SATB2 | DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2) | 5 | UniProt NCBI |
| NHLRC1 | E3 ubiquitin-protein ligase NHLRC1 (EC 2.3.2.27) (Malin) (NHL repeat-containing protein 1) (RING-type E3 ubiquitin transferase NHLRC1) | 5 | UniProt NCBI |
| TRIM47 | E3 ubiquitin-protein ligase TRIM47 (EC 2.3.2.27) (Gene overexpressed in astrocytoma protein) (RING finger protein 100) (Tripartite motif-containing protein 47) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0002121 | 0.00260627971198 | 0.75 | SATB1 SATB2 NHLRC1 | Generalized non-motor (absence) seizure |
| HP:0033259 | 0.00371547168799 | 0.75 | SATB1 SATB2 NHLRC1 | Non-motor seizure |
| HP:0011146 | 0.00698923937258 | 0.75 | SATB1 SATB2 NHLRC1 | Dialeptic seizure |
| HP:0002197 | 0.0179553160304 | 0.75 | SATB1 SATB2 NHLRC1 | Generalized-onset seizure |
| REAC:R-HSA-4551638 | 0.0218635493976 | 0.5 | SATB1 SATB2 | SUMOylation of chromatin organization proteins |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SATB1 | SATB2 | 0.998 | 0.208 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| SATB1 | TRIM47 | 0.997 | 0.036 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SATB2 | TRIM47 | 0.995 | 0.036 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NHLRC1 | TRIM47 | 0.994 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes