hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00710.1
Complex Portal: CPX-11478
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SH2B2 | SH2B adapter protein 2 (Adapter protein with pleckstrin homology and Src homology 2 domains) (SH2 and PH domain-containing adapter protein APS) | 5 | UniProt NCBI |
| ACSS2 | Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acetyl-CoA synthetase 1) (AceCS1) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme) (Propionate--CoA ligase) (EC 6.2.1.17) | 5 | UniProt NCBI |
| ELF2 | ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor) | 5 | UniProt NCBI |
| PRPS2 | Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase II) (PRS-II) | 5 | UniProt NCBI |
| TJP3 | Tight junction protein ZO-3 (Tight junction protein 3) (Zona occludens protein 3) (Zonula occludens protein 3) | 5 | UniProt NCBI |
| IRF6 | Interferon regulatory factor 6 (IRF-6) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP521 | 0.0429732972479 | 0.2 | ACSS2 | Amino acid conjugation of benzoic acid |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PRPS2 | ELF2 | 0.997 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | ||
| PRPS2 | ACSS2 | 0.994 | 0.034 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 fraction | |
| TJP3 | PRPS2 | 0.983 | 0.032 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PRPS2 | IRF6 | 0.982 | 0.120217391304 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SH2B2 | PRPS2 | 0.978 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SH2B2 | ACSS2 | 0.946 | bioplex3_WMM WMM_only | ||
| ACSS2 | IRF6 | 0.902 | 0.126 | bioplex3_WMM WMM_only | |
| SH2B2 | IRF6 | 0.902 | bioplex3_WMM WMM_only | ||
| ACSS2 | ELF2 | 0.757 | bioplex3_WMM WMM_only | ||
| SH2B2 | ELF2 | 0.757 | bioplex3_WMM WMM_only | ||
| ELF2 | IRF6 | 0.715 | bioplex3_WMM WMM_only | ||
| SH2B2 | TJP3 | 0.698 | bioplex3_WMM WMM_only | ||
| TJP3 | IRF6 | 0.698 | 0.1 | bioplex3_WMM WMM_only | |
| TJP3 | ACSS2 | 0.698 | 0.062 | bioplex3_WMM WMM_only | |
| TJP3 | ELF2 | 0.675 | bioplex3_WMM WMM_only |
Related Complexes