hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00731.1
Complex Portal: CPX-11776
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCNC1 | Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) | 5 | UniProt NCBI |
| KCNC3 | Potassium voltage-gated channel subfamily C member 3 (KSHIIID) (Voltage-gated potassium channel subunit Kv3.3) | 5 | UniProt NCBI |
| ATF6B | Cyclic AMP-dependent transcription factor ATF-6 beta (cAMP-dependent transcription factor ATF-6 beta) (Activating transcription factor 6 beta) (ATF6-beta) (Protein G13) (cAMP response element-binding protein-related protein) (Creb-rp) (cAMP-responsive element-binding protein-like 1) [Cleaved into: Processed cyclic AMP-dependent transcription factor ATF-6 beta] | 5 | UniProt NCBI |
| TNS1 | Tensin-1 (EC 3.1.3.-) | 5 | UniProt NCBI |
| PAX6 | Paired box protein Pax-6 (Aniridia type II protein) (Oculorhombin) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1296072 | 0.00332479301982 | 0.5 | KCNC1 KCNC3 | Voltage gated Potassium channels |
| REAC:R-HSA-1296071 | 0.0218635493976 | 0.5 | KCNC1 KCNC3 | Potassium Channels |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| KCNC3 | TNS1 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KCNC3 | ATF6B | 0.992 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KCNC3 | PAX6 | 0.984 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| KCNC1 | KCNC3 | 0.976 |
mutually_exclusive (Q03721)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| ATF6B | TNS1 | 0.675 | 0.048 | bioplex3_WMM WMM_only | |
| KCNC1 | PAX6 | 0.278 | bioplex3_WMM WMM_only | ||
| KCNC1 | TNS1 | 0.214 | bioplex3_WMM WMM_only | ||
| TNS1 | PAX6 | 0.214 | bioplex3_WMM WMM_only | ||
| KCNC1 | ATF6B | 0.078 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ATF6B | PAX6 | 0.032 | bioplex3_WMM WMM_only |
Related Complexes