hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00751.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PPA1 | Inorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase) | 4 | UniProt NCBI |
| ATIC | Bifunctional purine biosynthesis protein ATIC (AICAR transformylase/inosine monophosphate cyclohydrolase) (ATIC) [Cleaved into: Bifunctional purine biosynthesis protein ATIC, N-terminally processed] [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR formyltransferase) (AICAR transformylase); Inosine 5'-monophosphate cyclohydrolase (IMP cyclohydrolase) (EC 3.5.4.10) (IMP synthase) (Inosinicase)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0641513 | 0.000195585133711 | 1.0 | PPA1 ATIC | endometrium; nonciliated glandular epithelial cells[High] |
| HPA:0641523 | 0.000227480555516 | 1.0 | PPA1 ATIC | endometrium; nonciliated luminal epithelial cells[High] |
| HPA:0641532 | 0.000358071244794 | 1.0 | PPA1 ATIC | endometrium; stromal fibroblasts[>=Medium] |
| HPA:0640202 | 0.000358071244794 | 1.0 | PPA1 ATIC | endometrium; endothelial cells[>=Medium] |
| HPA:0640201 | 0.000400799074005 | 1.0 | PPA1 ATIC | endometrium; endothelial cells[>=Low] |
| HPA:0641512 | 0.000423065689227 | 1.0 | PPA1 ATIC | endometrium; nonciliated glandular epithelial cells[>=Medium] |
| HPA:0640692 | 0.000423065689227 | 1.0 | PPA1 ATIC | endometrium; smooth muscle cells[>=Medium] |
| HPA:0641522 | 0.000423065689227 | 1.0 | PPA1 ATIC | endometrium; nonciliated luminal epithelial cells[>=Medium] |
| HPA:0641503 | 0.000423065689227 | 1.0 | PPA1 ATIC | endometrium; ciliated epithelial cells[High] |
| HPA:0641531 | 0.000445934104861 | 1.0 | PPA1 ATIC | endometrium; stromal fibroblasts[>=Low] |
| HPA:0641511 | 0.00067883086408 | 1.0 | PPA1 ATIC | endometrium; nonciliated glandular epithelial cells[>=Low] |
| HPA:0641521 | 0.000737205503987 | 1.0 | PPA1 ATIC | endometrium; nonciliated luminal epithelial cells[>=Low] |
| HPA:0640691 | 0.000767295524558 | 1.0 | PPA1 ATIC | endometrium; smooth muscle cells[>=Low] |
| HPA:0641502 | 0.000797987345541 | 1.0 | PPA1 ATIC | endometrium; ciliated epithelial cells[>=Medium] |
| HPA:0641501 | 0.0011753162035 | 1.0 | PPA1 ATIC | endometrium; ciliated epithelial cells[>=Low] |
| HPA:0640000 | 0.00257450216005 | 1.0 | PPA1 ATIC | endometrium |
| HPA:0471482 | 0.00316125756118 | 1.0 | PPA1 ATIC | skin 2; sebaceous glands[>=Medium] |
| HPA:0471481 | 0.00458932993748 | 1.0 | PPA1 ATIC | skin 2; sebaceous glands[>=Low] |
| HPA:0471451 | 0.0103539760784 | 1.0 | PPA1 ATIC | skin 2; hair follicles[>=Low] |
| HPA:0091072 | 0.010465910955 | 1.0 | PPA1 ATIC | cerebellum; white matter cells - cytoplasm/membrane[>=Medium] |
| HPA:0090972 | 0.010465910955 | 1.0 | PPA1 ATIC | cerebellum; granular cells - cytoplasm/membrane[>=Medium] |
| HPA:0471491 | 0.0158484138347 | 1.0 | PPA1 ATIC | skin 2; vascular mural cells[>=Low] |
| HPA:0091071 | 0.0176947374969 | 1.0 | PPA1 ATIC | cerebellum; white matter cells - cytoplasm/membrane[>=Low] |
| HPA:0090971 | 0.0179878142973 | 1.0 | PPA1 ATIC | cerebellum; granular cells - cytoplasm/membrane[>=Low] |
| HPA:0091001 | 0.0253929683598 | 1.0 | PPA1 ATIC | cerebellum; molecular layer cells - cytoplasm/membrane[>=Low] |
| KEGG:00670 | 0.0356198329076 | 0.5 | ATIC | One carbon pool by folate |
| HP:0034565 | 0.0499436884913 | 0.5 | ATIC | Elevated urinary 5-amino-4-imidazolecarboxamide-riboside level |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PPA1 | ATIC | 0.981 | 0.254 | bioplex_WMM bioplex3_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| PPA1 | huMAP3_00751.1 huMAP3_11534.1 huMAP3_12823.1 huMAP3_13343.1 huMAP3_14442.1 |
| ATIC | huMAP3_00751.1 huMAP3_12823.1 huMAP3_14442.1 |