hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
NUDT18	8-oxo-dGDP phosphatase NUDT18 (EC 3.6.1.58) (2-hydroxy-dADP phosphatase) (7,8-dihydro-8-oxoguanine phosphatase) (MutT homolog 3) (Nucleoside diphosphate-linked moiety X motif 18) (Nudix motif 18)	5	UniProt NCBI
FCN1	Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin)	5	UniProt NCBI
FCN2	Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35)	5	UniProt NCBI
C8orf58	Uncharacterized protein C8orf58	2	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-2855086	3.07549051138e-05	0.5	FCN2 FCN1	Ficolins bind to repetitive carbohydrate structures on the target cell surface
REAC:R-HSA-166662	0.000153732433522	0.5	FCN2 FCN1	Lectin pathway of complement activation
REAC:R-HSA-166786	0.000461028962628	0.5	FCN2 FCN1	Creation of C4 and C2 activators
REAC:R-HSA-166663	0.00122873738811	0.5	FCN2 FCN1	Initial triggering of complement
WP:WP2806	0.00742144474402	0.5	FCN2 FCN1	Complement system
WP:WP5090	0.00992155513194	0.5	FCN2 FCN1	Complement system in neuronal development and plasticity
REAC:R-HSA-166658	0.0115164156767	0.5	FCN2 FCN1	Complement cascade
GO:0043654	0.0168521501606	0.5	FCN2 FCN1	recognition of apoptotic cell

Protein 1	Protein 2	Score	Evidence
FCN1	FCN2	1.0	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
NUDT18	FCN1	0.995	bioplex3_WMM bioplex3_HCT116 WMM_only
FCN1	C8orf58	0.972	bioplex3_WMM bioplex3_HCT116 WMM_only
NUDT18	FCN2	0.902	bioplex3_WMM WMM_only

Genename	Complexes
NUDT18	huMAP3_00762.1 huMAP3_11349.1 huMAP3_11697.1 huMAP3_13107.1 huMAP3_14792.1
FCN1	huMAP3_00762.1 huMAP3_11349.1 huMAP3_13107.1
FCN2	huMAP3_00762.1 huMAP3_11349.1 huMAP3_11697.1 huMAP3_14792.1 huMAP3_15183.1
C8orf58	huMAP3_00762.1 huMAP3_11170.1 huMAP3_11377.1 huMAP3_11473.1 huMAP3_13107.1