hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00773.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UQCRH | Cytochrome b-c1 complex subunit 6, mitochondrial (Complex III subunit 6) (Complex III subunit VIII) (Cytochrome c1 non-heme 11 kDa protein) (Mitochondrial hinge protein) (Ubiquinol-cytochrome c reductase complex 11 kDa protein) | 5 | UniProt NCBI |
| UQCRC2 | Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2) | 5 | UniProt NCBI |
| MT-CO2 | Cytochrome c oxidase subunit 2 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide II) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04260 | 0.000415528139074 | 1.0 | UQCRH MT-CO2 | Cardiac muscle contraction |
| KEGG:00190 | 0.00119992691491 | 1.0 | UQCRH MT-CO2 | Oxidative phosphorylation |
| KEGG:04932 | 0.00155920593969 | 1.0 | UQCRH MT-CO2 | Non-alcoholic fatty liver disease |
| WP:WP111 | 0.00202305274778 | 1.0 | UQCRH MT-CO2 | Electron transport chain OXPHOS system in mitochondria |
| KEGG:05415 | 0.00267768543767 | 1.0 | UQCRH MT-CO2 | Diabetic cardiomyopathy |
| KEGG:05208 | 0.0033003273675 | 1.0 | UQCRH MT-CO2 | Chemical carcinogenesis - reactive oxygen species |
| KEGG:04714 | 0.00339933231144 | 1.0 | UQCRH MT-CO2 | Thermogenesis |
| WP:WP4396 | 0.00396523446209 | 1.0 | UQCRH MT-CO2 | Nonalcoholic fatty liver disease |
| KEGG:05012 | 0.00458495309323 | 1.0 | UQCRH MT-CO2 | Parkinson disease |
| KEGG:05020 | 0.00485920816781 | 1.0 | UQCRH MT-CO2 | Prion disease |
| KEGG:05016 | 0.00594761227231 | 1.0 | UQCRH MT-CO2 | Huntington disease |
| REAC:R-HSA-611105 | 0.00828920325958 | 1.0 | UQCRH MT-CO2 | Respiratory electron transport |
| HP:0001733 | 0.00849254590808 | 1.0 | UQCRH MT-CO2 | Pancreatitis |
| KEGG:05014 | 0.00850662183301 | 1.0 | UQCRH MT-CO2 | Amyotrophic lateral sclerosis |
| KEGG:05010 | 0.0093688914925 | 1.0 | UQCRH MT-CO2 | Alzheimer disease |
| REAC:R-HSA-163200 | 0.0124056103205 | 1.0 | UQCRH MT-CO2 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| KEGG:05022 | 0.0138982457502 | 1.0 | UQCRH MT-CO2 | Pathways of neurodegeneration - multiple diseases |
| REAC:R-HSA-1428517 | 0.0242575818332 | 1.0 | UQCRH MT-CO2 | The citric acid (TCA) cycle and respiratory electron transport |
| HP:0012091 | 0.0351868219998 | 1.0 | UQCRH MT-CO2 | Abnormality of pancreas physiology |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| UQCRC2 | MT-CO2 | 0.998 | 0.83 | bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM boldt fraction boldt_WMM |
| UQCRH | UQCRC2 | 0.978 | 0.686 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt fraction boldt_WMM |
| UQCRH | MT-CO2 | 0.561 | 0.36 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt fraction boldt_WMM |
Related Complexes