hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00803.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PTBP1 | Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) | 5 | UniProt NCBI |
| AJUBA | LIM domain-containing protein ajuba | 5 | UniProt NCBI |
| PTPN21 | Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1) | 5 | UniProt NCBI |
| LATS2 | Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04392 | 0.000247823846667 | 0.666666666667 | AJUBA LATS2 | Hippo signaling pathway - multiple species |
| WP:WP4541 | 0.00514316015145 | 0.666666666667 | AJUBA LATS2 | Hippo Merlin signaling dysregulation |
| KEGG:04390 | 0.00802719593767 | 0.666666666667 | AJUBA LATS2 | Hippo signaling pathway |
| CORUM:6237 | 0.0499402709677 | 0.333333333333 | AJUBA | AJUBA-GFI1-HDAC1 complex |
| CORUM:6243 | 0.0499402709677 | 0.333333333333 | AJUBA | AJUBA-GFI1-HDAC2 complex |
| CORUM:6244 | 0.0499402709677 | 0.333333333333 | AJUBA | AJUBA-GFI1-HDAC3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| AJUBA | PTPN21 | 0.997 | 0.116 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| AJUBA | LATS2 | 0.996 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PTBP1 | AJUBA | 0.955 | 0.19 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| PTPN21 | LATS2 | 0.73 | bioplex3_WMM WMM_only | |
| PTBP1 | PTPN21 | 0.086 | 0.242 | bioplex_WMM bioplex3_WMM WMM_only |
| PTBP1 | LATS2 | 0.007 | bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes