hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00837.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAGOH | Protein mago nashi homolog | 5 | UniProt NCBI |
| PNN | Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein) | 5 | UniProt NCBI |
| RBM8A | RNA-binding protein 8A (Binder of OVCA1-1) (BOV-1) (RNA-binding motif protein 8A) (RNA-binding protein Y14) (Ribonucleoprotein RBM8A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:773 | 3.41752350426e-06 | 0.666666666667 | MAGOH RBM8A | Y14-Magoh complex |
| CORUM:763 | 3.41752350426e-06 | 0.666666666667 | MAGOH RBM8A | Y14-Magoh complex |
| KEGG:03015 | 6.34627347292e-06 | 1.0 | MAGOH PNN RBM8A | mRNA surveillance pathway |
| KEGG:03013 | 8.70565480728e-06 | 1.0 | MAGOH PNN RBM8A | Nucleocytoplasmic transport |
| CORUM:1293 | 1.02521027753e-05 | 0.666666666667 | MAGOH RBM8A | IPO13-RBM8A-MAGOH complex |
| CORUM:1181 | 1.71074963619e-05 | 1.0 | MAGOH PNN RBM8A | C complex spliceosome |
| CORUM:769 | 2.05032700758e-05 | 0.666666666667 | MAGOH RBM8A | Exon junction complex (EIF4A3, MLN51, MAGOH, Y14) |
| CORUM:754 | 2.05032700758e-05 | 0.666666666667 | MAGOH RBM8A | Exon junction complex (EIF4A3, MLN51, UPF3B, MAGOH, Y14) |
| CORUM:744 | 2.05032700758e-05 | 0.666666666667 | MAGOH RBM8A | Exon junction complex (EIF4A3, MLN51, MAGOH, Y14) |
| CORUM:740 | 2.05032700758e-05 | 0.666666666667 | MAGOH RBM8A | Exon junction complex (EIF4A3, MLN51, MAGOH, Y14) |
| CORUM:755 | 3.41705576683e-05 | 0.666666666667 | MAGOH RBM8A | Exon junction complex (EIF4A3, MLN51, UPF3B, MAGOH, Y14, PYM) |
| CORUM:6742 | 5.12534978153e-05 | 0.666666666667 | MAGOH RBM8A | SMG1-UPF2-Y14-MAGOH-UPF3B-EIF4A3 complex |
| CORUM:785 | 7.17516227795e-05 | 0.666666666667 | MAGOH RBM8A | Exon junction complex |
| GO:0035145 | 0.000109576846827 | 1.0 | MAGOH PNN RBM8A | exon-exon junction complex |
| REAC:R-HSA-72163 | 0.000622120634792 | 1.0 | MAGOH PNN RBM8A | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.000689757414765 | 1.0 | MAGOH PNN RBM8A | mRNA Splicing |
| REAC:R-HSA-72203 | 0.00158225905908 | 1.0 | MAGOH PNN RBM8A | Processing of Capped Intron-Containing Pre-mRNA |
| GO:1903503 | 0.00421361424067 | 0.666666666667 | MAGOH RBM8A | ATPase inhibitor complex |
| GO:1990501 | 0.00421361424067 | 0.666666666667 | MAGOH RBM8A | exon-exon junction subcomplex mago-y14 |
| KEGG:03040 | 0.00588292524774 | 0.666666666667 | MAGOH RBM8A | Spliceosome |
| HPA:0090183 | 0.00681655925187 | 1.0 | MAGOH PNN RBM8A | cerebellum; cells in granular layer[High] |
| REAC:R-HSA-72187 | 0.0101009261622 | 0.666666666667 | MAGOH RBM8A | mRNA 3'-end processing |
| GO:0071013 | 0.0101882437539 | 1.0 | MAGOH PNN RBM8A | catalytic step 2 spliceosome |
| REAC:R-HSA-73856 | 0.0132793882188 | 0.666666666667 | MAGOH RBM8A | RNA Polymerase II Transcription Termination |
| REAC:R-HSA-159236 | 0.0164154902665 | 0.666666666667 | MAGOH RBM8A | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| REAC:R-HSA-72202 | 0.0209338694285 | 0.666666666667 | MAGOH RBM8A | Transport of Mature Transcript to Cytoplasm |
| HPA:0620223 | 0.0245360663978 | 1.0 | MAGOH PNN RBM8A | vagina; squamous epithelial cells[High] |
| REAC:R-HSA-8953854 | 0.0247774527734 | 1.0 | MAGOH PNN RBM8A | Metabolism of RNA |
| CORUM:351 | 0.0316415640819 | 0.666666666667 | MAGOH RBM8A | Spliceosome |
| REAC:R-HSA-975957 | 0.0436932800731 | 0.666666666667 | MAGOH RBM8A | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
| REAC:R-HSA-927802 | 0.0436932800731 | 0.666666666667 | MAGOH RBM8A | Nonsense-Mediated Decay (NMD) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MAGOH | RBM8A | 1.0 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM treiber_WMM | |
| PNN | RBM8A | 0.999 | 0.874 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM treiber_WMM |
| MAGOH | PNN | 0.982 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM |
Related Complexes