hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_00849.1

Complex Portal: CPX-21377

Confidence: Extremely High

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Genename	Protein Name	Uniprot Annotation Score	Links
ALKBH4	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (Alkylated DNA repair protein alkB homolog 4) (DNA N6-methyl adenine demethylase ALKBH4) (EC 1.14.11.51) (Lysine-specific demethylase ALKBH4) (EC 1.14.11.-)	5	UniProt NCBI
LRWD1	Leucine-rich repeat and WD repeat-containing protein 1 (Centromere protein 33) (CENP-33) (Origin recognition complex-associated protein) (ORC-associated protein) (ORCA)	5	UniProt NCBI
ORC2	Origin recognition complex subunit 2	5	UniProt NCBI
ORC3	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo)	5	UniProt NCBI

Showing 1 to 4 of 4 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:1032	1.53774525569e-05	0.5	ORC2 ORC3	ORC 2-4 complex (origin recognition 2-4 complex)
GO:0000808	2.15253635486e-05	0.75	ORC3 ORC2 LRWD1	origin recognition complex
GO:0005664	2.15253635486e-05	0.75	ORC3 ORC2 LRWD1	nuclear origin of replication recognition complex
CORUM:5251	3.07520988333e-05	0.5	ORC2 ORC3	Ku-ORC complex
CORUM:1034	3.07520988333e-05	0.5	ORC2 ORC3	ORC 2-5 complex (origin recognition 2-5 complex)
CORUM:1038	5.12488211613e-05	0.5	ORC2 ORC3	ORC 1-5 complex (origin recognition 1-5 complex)
CORUM:1033	7.68662167609e-05	0.5	ORC2 ORC3	ORC complex (origin recognition complex)
CORUM:1031	7.68662167609e-05	0.5	ORC2 ORC3	ORC complex (origin recognition complex)
CORUM:389	7.68662167609e-05	0.5	ORC2 ORC3	ORC complex (origin recognition complex)
REAC:R-HSA-68689	0.000286914834749	0.5	ORC2 ORC3	CDC6 association with the ORC:origin complex

Showing 1 to 10 of 22 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
ORC2	LRWD1	1.0	0.22		hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () Malo gupta_WMM fraction
ALKBH4	ORC3	0.999			bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
ALKBH4	ORC2	0.999	0.02		bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
ORC2	ORC3	0.995			bioplex_WMM bioplex3_WMM youn_WMM Malo gupta_WMM fraction
ALKBH4	LRWD1	0.991	0.076		bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
LRWD1	ORC3	0.858			bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only

Showing 1 to 6 of 6 entries

Related Complexes

Genename	Complexes
ALKBH4	huMAP3_00849.1 huMAP3_07945.1 huMAP3_08307.1 huMAP3_08390.1 huMAP3_09702.1 huMAP3_09909.1 huMAP3_11544.1 huMAP3_11720.1 huMAP3_11726.1 huMAP3_12035.1
ORC2	huMAP3_00849.1 huMAP3_04759.1 huMAP3_06528.1 huMAP3_07727.1 huMAP3_08307.1 huMAP3_09315.1 huMAP3_09702.1 huMAP3_09909.1 huMAP3_11544.1 huMAP3_11720.1 huMAP3_11726.1 huMAP3_12035.1
LRWD1	huMAP3_00849.1 huMAP3_06528.1 huMAP3_08993.1 huMAP3_09315.1 huMAP3_09702.1 huMAP3_09909.1 huMAP3_11720.1 huMAP3_11726.1 huMAP3_12035.1
ORC3	huMAP3_00849.1 huMAP3_04759.1 huMAP3_06528.1 huMAP3_08307.1 huMAP3_08390.1 huMAP3_09702.1 huMAP3_09909.1 huMAP3_11544.1 huMAP3_11720.1 huMAP3_11726.1 huMAP3_12035.1