hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00887.1
Complex Portal: CPX-17353
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RHOA | Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12) | 5 | UniProt NCBI |
| XPNPEP1 | Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble) | 5 | UniProt NCBI |
| RHOC | Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5666185 | 0.00024538606603 | 0.666666666667 | RHOA RHOC | RHO GTPases Activate Rhotekin and Rhophilins |
| REAC:R-HSA-5627117 | 0.0011650518872 | 0.666666666667 | RHOA RHOC | RHO GTPases Activate ROCKs |
| REAC:R-HSA-5625900 | 0.0011650518872 | 0.666666666667 | RHOA RHOC | RHO GTPases activate CIT |
| REAC:R-HSA-416572 | 0.0011650518872 | 0.666666666667 | RHOA RHOC | Sema4D induced cell migration and growth-cone collapse |
| GO:1902766 | 0.00140460216025 | 0.666666666667 | RHOA RHOC | skeletal muscle satellite cell migration |
| REAC:R-HSA-400685 | 0.00172341693863 | 0.666666666667 | RHOA RHOC | Sema4D in semaphorin signaling |
| WP:WP2431 | 0.00451842523141 | 0.666666666667 | RHOA RHOC | Spinal cord injury |
| WP:WP4217 | 0.00751610583681 | 0.666666666667 | RHOA RHOC | Ebola virus infection in host |
| REAC:R-HSA-373755 | 0.0116360425406 | 0.666666666667 | RHOA RHOC | Semaphorin interactions |
| REAC:R-HSA-416482 | 0.0128584085686 | 0.666666666667 | RHOA RHOC | G alpha (12/13) signalling events |
| REAC:R-HSA-9013106 | 0.0141416283812 | 0.666666666667 | RHOA RHOC | RHOC GTPase cycle |
| REAC:R-HSA-5625740 | 0.0220121799777 | 0.666666666667 | RHOA RHOC | RHO GTPases activate PKNs |
| CORUM:553 | 0.0499402709677 | 0.333333333333 | RHOA | RHOA-IP3R-TRPC1 complex |
| CORUM:816 | 0.0499402709677 | 0.333333333333 | RHOA | MRIP-RHOA complex |
| CORUM:3153 | 0.0499402709677 | 0.333333333333 | RHOA | GNAQ-GEFT-RHOA complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RHOC | RHOA | 0.989 | 0.838 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| XPNPEP1 | RHOA | 0.977 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| XPNPEP1 | RHOC | 0.169 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes