hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00888.1
Complex Portal: CPX-12553
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LYRM4 | LYR motif-containing protein 4 | 5 | UniProt NCBI |
| CARTPT | Cocaine- and amphetamine-regulated transcript protein [Cleaved into: CART(1-39); CART(42-89)] | 5 | UniProt NCBI |
| EFCAB13 | EF-hand calcium-binding domain-containing protein 13 | 3 | UniProt NCBI |
| NFS1 | Cysteine desulfurase (EC 2.8.1.7) | 5 | UniProt NCBI |
| CDNF | Cerebral dopamine neurotrophic factor (ARMET-like protein 1) (Conserved dopamine neurotrophic factor) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5152 | 0.000534376000489 | 0.4 | NFS1 LYRM4 | Iron sulfur cluster biogenesis |
| GO:0099128 | 0.0140440992017 | 0.4 | NFS1 LYRM4 | mitochondrial iron-sulfur cluster assembly complex |
| HP:0003648 | 0.0176485923371 | 0.4 | NFS1 LYRM4 | Lacticaciduria |
| GO:0044572 | 0.0280843539964 | 0.4 | NFS1 LYRM4 | [4Fe-4S] cluster assembly |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| LYRM4 | NFS1 | 1.0 | 0.932 | bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 fraction boldt_WMM | |
| LYRM4 | EFCAB13 | 0.984 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| CDNF | NFS1 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| LYRM4 | CDNF | 0.956 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| LYRM4 | CARTPT | 0.952 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| NFS1 | CARTPT | 0.91 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| EFCAB13 | NFS1 | 0.814 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| LYRM4 | huMAP3_00863.1 huMAP3_00888.1 huMAP3_07085.1 |
| CARTPT | huMAP3_00888.1 huMAP3_04699.1 huMAP3_04759.1 huMAP3_08307.1 huMAP3_09909.1 huMAP3_11544.1 huMAP3_11726.1 huMAP3_12035.1 |
| EFCAB13 | huMAP3_00863.1 huMAP3_00888.1 |
| NFS1 | huMAP3_00863.1 huMAP3_00888.1 huMAP3_07085.1 |
| CDNF | huMAP3_00863.1 huMAP3_00888.1 huMAP3_07085.1 |