hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00895.1
Complex Portal: CPX-19583
Confidence: Extremely High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ABCB9 | ABC-type oligopeptide transporter ABCB9 (EC 7.4.2.6) (ATP-binding cassette sub-family B member 9) (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL) | 5 | UniProt   NCBI |
| POR | NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4) | 5 | UniProt   NCBI |
| CLCN4 | H(+)/Cl(-) exchange transporter 4 (Chloride channel protein 4) (ClC-4) (Chloride transporter ClC-4) | 5 | UniProt   NCBI |
| ARFGEF1 | Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1) | 5 | UniProt   NCBI |
| CLCN5 | H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5) | 5 | UniProt   NCBI |
| TMEM9B | Transmembrane protein 9B | 5 | UniProt   NCBI |
| ABCA3 | Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ABC-C transporter) (ATP-binding cassette sub-family A member 3) (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   KEGG:02010 | 0.00405482051627 | 0.333333333333 | ABCA3 ABCB9 | ABC transporters |
|   REAC:R-HSA-382551 | 0.00454956863803 | 0.666666666667 | ABCA3 CLCN4 ABCB9 CLCN5 | Transport of small molecules |
|   GO:0098588 | 0.046464555054 | 1.0 | ARFGEF1 CLCN5 ABCB9 CLCN4 ABCA3 TMEM9B | bounding membrane of organelle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  ABCA3 |  TMEM9B | 0.999 | 0.114           |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
|  CLCN5 |  TMEM9B | 0.999 | 0.174           |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
|  ARFGEF1 |  TMEM9B | 0.994 | 0.058           |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
|  CLCN4 |  TMEM9B | 0.982 |            |
structurally_consistent (dimer)        
|
bioplex3_WMM     bioplex3_HCT116     WMM_only     |
|  ABCB9 |  TMEM9B | 0.981 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  POR |  TMEM9B | 0.968 | 0.07           |          | bioplex3_WMM     bioplex3_HCT116     WMM_only     |
|  ABCA3 |  ARFGEF1 | 0.717 | 0.054           |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  ABCA3 |  POR | 0.663 | 0.056           |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  ARFGEF1 |  CLCN5 | 0.652 | 0.168           |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  CLCN4 |  ARFGEF1 | 0.633 |            |          | bioplex3_WMM     WMM_only     |
|  CLCN4 |  CLCN5 | 0.633 |            |          | bioplex3_WMM     WMM_only     |
|  ABCA3 |  CLCN4 | 0.545 |            |          | bioplex3_WMM     WMM_only     |
|  ABCA3 |  ABCB9 | 0.458 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  ABCA3 |  CLCN5 | 0.374 | 0.072           |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  ABCB9 |  POR | 0.266 |            |          | bioplex_WMM     bioplex3_WMM     youn_WMM     WMM_only     |
|  ABCB9 |  CLCN5 | 0.159 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  POR |  CLCN4 | 0.093 |            |          | bioplex3_WMM     WMM_only     |
|  POR |  CLCN5 | 0.064 | 0.146           |          | bioplex3_WMM     WMM_only     |
|  ABCB9 |  CLCN4 | 0.042 |            |          | bioplex3_WMM     WMM_only     |
|  POR |  ARFGEF1 | 0.03 | 0.064           |          | bioplex3_WMM     WMM_only     |
|  ABCB9 |  ARFGEF1 | 0.012 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
Related Complexes