hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00911.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
UPRT | Uracil phosphoribosyltransferase homolog | 5 | UniProt   NCBI |
UCK2 | Uridine-cytidine kinase 2 (UCK 2) (EC 2.7.1.48) (Cytidine monophosphokinase 2) (Testis-specific protein TSA903) (Uridine monophosphokinase 2) | 5 | UniProt   NCBI |
UCKL1 | Uridine-cytidine kinase-like 1 (EC 2.7.1.48) | 5 | UniProt   NCBI |
UCK1 | Uridine-cytidine kinase 1 (UCK 1) (EC 2.7.1.48) (Cytidine monophosphokinase 1) (Uridine monophosphokinase 1) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-73614 | 2.31434954766e-07 | 0.75 | UCK2 UCKL1 UCK1 | Pyrimidine salvage |
  GO:0004849 | 1.53784171933e-06 | 0.75 | UCK2 UCKL1 UCK1 | uridine kinase activity |
  REAC:R-HSA-8956321 | 1.86454808481e-06 | 0.75 | UCK2 UCKL1 UCK1 | Nucleotide salvage |
  GO:0008655 | 3.84440695359e-06 | 0.75 | UCK2 UCKL1 UCK1 | pyrimidine-containing compound salvage |
  KEGG:00240 | 4.86072516083e-06 | 0.75 | UCK2 UCKL1 UCK1 | Pyrimidine metabolism |
  KEGG:00983 | 1.63910874597e-05 | 0.75 | UCK2 UCKL1 UCK1 | Drug metabolism - other enzymes |
  KEGG:01232 | 1.8726845031e-05 | 0.75 | UCK2 UCKL1 UCK1 | Nucleotide metabolism |
  GO:0019206 | 3.22863876272e-05 | 0.75 | UCK2 UCKL1 UCK1 | nucleoside kinase activity |
  REAC:R-HSA-15869 | 0.000102255107087 | 0.75 | UCK2 UCKL1 UCK1 | Metabolism of nucleotides |
  GO:0072528 | 0.000372255315939 | 0.75 | UCK2 UCKL1 UCK1 | pyrimidine-containing compound biosynthetic process |
  GO:0043094 | 0.000777349058504 | 0.75 | UCK2 UCKL1 UCK1 | cellular metabolic compound salvage |
  WP:WP1601 | 0.00103429913449 | 0.5 | UCK2 UCK1 | Fluoropyrimidine activity |
  GO:0019205 | 0.00229706847948 | 0.75 | UCK2 UCKL1 UCK1 | nucleobase-containing compound kinase activity |
  GO:0010138 | 0.0028092043205 | 0.5 | UCK2 UCK1 | pyrimidine ribonucleotide salvage |
  GO:0044206 | 0.0028092043205 | 0.5 | UCK2 UCK1 | UMP salvage |
  GO:0044211 | 0.0028092043205 | 0.5 | UCK2 UCK1 | CTP salvage |
  GO:0032262 | 0.0028092043205 | 0.5 | UCK2 UCK1 | pyrimidine nucleotide salvage |
  GO:0072527 | 0.0079870728422 | 0.75 | UCK2 UCKL1 UCK1 | pyrimidine-containing compound metabolic process |
  GO:0043771 | 0.00842684400117 | 0.5 | UCK2 UCK1 | cytidine kinase activity |
  GO:0009174 | 0.0168521501606 | 0.5 | UCK2 UCK1 | pyrimidine ribonucleoside monophosphate biosynthetic process |
  GO:0009173 | 0.0168521501606 | 0.5 | UCK2 UCK1 | pyrimidine ribonucleoside monophosphate metabolic process |
  GO:0046049 | 0.0168521501606 | 0.5 | UCK2 UCK1 | UMP metabolic process |
  GO:0006241 | 0.0168521501606 | 0.5 | UCK2 UCK1 | CTP biosynthetic process |
  GO:0006222 | 0.0168521501606 | 0.5 | UCK2 UCK1 | UMP biosynthetic process |
  GO:0009209 | 0.0280843539964 | 0.5 | UCK2 UCK1 | pyrimidine ribonucleoside triphosphate biosynthetic process |
  GO:0046036 | 0.042122686785 | 0.5 | UCK2 UCK1 | CTP metabolic process |
  GO:0009148 | 0.042122686785 | 0.5 | UCK2 UCK1 | pyrimidine nucleoside triphosphate biosynthetic process |
  GO:0009130 | 0.042122686785 | 0.5 | UCK2 UCK1 | pyrimidine nucleoside monophosphate biosynthetic process |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 UPRT |  UCKL1 | 1.0 | 0.216           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 UCK2 |  UCK1 | 1.0 | 0.484           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 UPRT |  UCK2 | 1.0 | 0.026           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 UCK2 |  UCKL1 | 0.999 | 0.124           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 UPRT |  UCK1 | 0.999 | 0.082           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 UCKL1 |  UCK1 | 0.993 | 0.15           | bioplex_WMM     bioplex3_WMM     WMM_only     |
Related Complexes
Genename | Complexes |
---|---|
UPRT | huMAP3_00911.1 huMAP3_11592.1 huMAP3_14114.1 huMAP3_14959.1 |
UCK2 | huMAP3_00911.1 |
UCKL1 | huMAP3_00911.1 huMAP3_11592.1 huMAP3_14114.1 huMAP3_14959.1 |
UCK1 | huMAP3_00911.1 huMAP3_11592.1 huMAP3_14114.1 huMAP3_14959.1 |