hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00964.1
Complex Portal: CPX-25415
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FNIP1 | Folliculin-interacting protein 1 | 5 | UniProt NCBI |
| FNIP2 | Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein) | 5 | UniProt NCBI |
| CPXCR1 | CPX chromosomal region candidate gene 1 protein (Cancer/testis antigen 77) (CT77) | 2 | UniProt NCBI |
| ZNF215 | Zinc finger protein 215 (BWSCR2-associated zinc finger protein 2) (BAZ-2) (Zinc finger protein with KRAB and SCAN domains 11) | 4 | UniProt NCBI |
| VTA1 | Vacuolar protein sorting-associated protein VTA1 homolog (Dopamine-responsive gene 1 protein) (DRG-1) (LYST-interacting protein 5) (LIP5) (SKD1-binding protein 1) (SBP1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9639288 | 0.0208015819243 | 0.4 | FNIP1 FNIP2 | Amino acids regulate mTORC1 |
| GO:0042030 | 0.0280843539964 | 0.4 | FNIP1 FNIP2 | ATPase inhibitor activity |
| KEGG:04150 | 0.0484667159694 | 0.4 | FNIP1 FNIP2 | mTOR signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| FNIP1 | FNIP2 | 0.997 |
mutually_exclusive (Q8NFG4)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| FNIP1 | VTA1 | 0.992 | 0.088 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FNIP2 | VTA1 | 0.991 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CPXCR1 | VTA1 | 0.978 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ZNF215 | VTA1 | 0.954 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes