hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00972.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PDE12 | 2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4) | 5 | UniProt NCBI |
| PNPLA8 | Calcium-independent phospholipase A2-gamma (EC 3.1.1.-) (EC 3.1.1.5) (Intracellular membrane-associated calcium-independent phospholipase A2 gamma) (iPLA2-gamma) (PNPLA-gamma) (Patatin-like phospholipase domain-containing protein 8) (iPLA2-2) | 5 | UniProt NCBI |
| EIF4G1 | Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1169410 | 0.017372320015 | 0.666666666667 | EIF4G1 PDE12 | Antiviral mechanism by IFN-stimulated genes |
| CORUM:1308 | 0.0499402709677 | 0.333333333333 | EIF4G1 | PABPC1-HSPA8-HNRPD-EIF4G1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PDE12 | PNPLA8 | 0.967 | 0.05 | hein_WMM bioplex3_WMM youn_WMM WMM_only |
| PNPLA8 | EIF4G1 | 0.961 | hein_WMM bioplex3_WMM WMM_only | |
| PDE12 | EIF4G1 | 0.048 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only treiber_WMM |
Related Complexes