hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00973.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| COA8 | Cytochrome c oxidase assembly factor 8 (COA8) (Apoptogenic protein 1, mitochondrial) (APOP-1) | 5 | UniProt NCBI |
| SUOX | Sulfite oxidase, mitochondrial (EC 1.8.3.1) | 5 | UniProt NCBI |
| COX10 | Protoheme IX farnesyltransferase, mitochondrial (EC 2.5.1.141) (Heme O synthase) | 5 | UniProt NCBI |
| SCRN1 | Secernin-1 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001942 | 0.0020342326718 | 0.75 | COA8 COX10 SUOX | Metabolic acidosis |
| HP:0003688 | 0.0108451581837 | 0.5 | COA8 COX10 | Cytochrome C oxidase-negative muscle fibers |
| HP:0001941 | 0.0337929626939 | 0.75 | COA8 COX10 SUOX | Acidosis |
| WP:WP5030 | 0.0373138951921 | 0.25 | SUOX | Ethylmalonic encephalopathy |
| HP:0004360 | 0.040406598238 | 0.75 | COA8 COX10 SUOX | Abnormality of acid-base homeostasis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| COA8 | COX10 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SUOX | COX10 | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SCRN1 | COX10 | 0.977 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SUOX | COA8 | 0.768 | bioplex3_WMM WMM_only | |
| SCRN1 | COA8 | 0.356 | bioplex3_WMM WMM_only | |
| SUOX | SCRN1 | 0.249 | 0.062 | bioplex3_WMM WMM_only |
Related Complexes