hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01001.1
Complex Portal: CPX-15491
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ARHGEF10 | Rho guanine nucleotide exchange factor 10 | 5 | UniProt NCBI |
| ARHGEF10L | Rho guanine nucleotide exchange factor 10-like protein (GrinchGEF) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-193648 | 0.00154301186217 | 1.0 | ARHGEF10 ARHGEF10L | NRAGE signals death through JNK |
| REAC:R-HSA-204998 | 0.0027271837564 | 1.0 | ARHGEF10 ARHGEF10L | Cell death signalling via NRAGE, NRIF and NADE |
| REAC:R-HSA-9013026 | 0.0031270340064 | 1.0 | ARHGEF10 ARHGEF10L | RHOB GTPase cycle |
| REAC:R-HSA-416482 | 0.00323126847328 | 1.0 | ARHGEF10 ARHGEF10L | G alpha (12/13) signalling events |
| REAC:R-HSA-9013106 | 0.00355422444443 | 1.0 | ARHGEF10 ARHGEF10L | RHOC GTPase cycle |
| REAC:R-HSA-193704 | 0.0046153654925 | 1.0 | ARHGEF10 ARHGEF10L | p75 NTR receptor-mediated signalling |
| REAC:R-HSA-8980692 | 0.013456498798 | 1.0 | ARHGEF10 ARHGEF10L | RHOA GTPase cycle |
| REAC:R-HSA-73887 | 0.0136718027788 | 1.0 | ARHGEF10 ARHGEF10L | Death Receptor Signaling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ARHGEF10 | ARHGEF10L | 0.998 | 0.102 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes