hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01004.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GNG3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 | 4 | UniProt NCBI |
| GNA12 | Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12) | 5 | UniProt NCBI |
| GNAZ | Guanine nucleotide-binding protein G(z) subunit alpha (G(x) alpha chain) (Gz-alpha) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-456926 | 0.000599775374997 | 1.0 | GNG3 GNA12 | Thrombin signalling through proteinase activated receptors (PARs) |
| WP:WP35 | 0.00127818796583 | 1.0 | GNG3 GNA12 | G protein signaling pathways |
| KEGG:05163 | 0.00298087791786 | 1.0 | GNG3 GNA12 | Human cytomegalovirus infection |
| REAC:R-HSA-416482 | 0.00323126847328 | 1.0 | GNG3 GNA12 | G alpha (12/13) signalling events |
| KEGG:05200 | 0.0161326036311 | 1.0 | GNG3 GNA12 | Pathways in cancer |
| CORUM:7154 | 0.0249718442457 | 0.5 | GNG3 | GNAS-L-GNB1-GNG3 complex |
| REAC:R-HSA-76002 | 0.0400465404229 | 1.0 | GNG3 GNA12 | Platelet activation, signaling and aggregation |
| CORUM:7026 | 0.0499419797295 | 0.5 | GNG3 | GNAI1-GNB3-GNG3 complex |
| CORUM:7152 | 0.0499419797295 | 0.5 | GNG3 | GNAS-L-GNB1-GNG3 complex |
| CORUM:7153 | 0.0499419797295 | 0.5 | GNG3 | GNAS-L-GNB2-GNG3 complex |
| CORUM:7155 | 0.0499419797295 | 0.5 | GNG3 | GNAS-L-GNB4-GNG3 complex |
| CORUM:7156 | 0.0499419797295 | 0.5 | GNG3 | GNAS-L-GNB5-GNG3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| GNAZ | GNA12 | 0.993 | 0.112 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| GNAZ | GNG3 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| GNG3 | GNA12 | 0.985 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes