hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01010.1
Complex Portal: CPX-19801
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PLEKHA7 | Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7) | 5 | UniProt NCBI |
| PI4KB | Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) (NPIK) (PI4K92) (PI4KIII) | 5 | UniProt NCBI |
| CRTC1 | CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1) | 5 | UniProt NCBI |
| SAMD4B | Protein Smaug homolog 2 (Smaug 2) (hSmaug2) (Sterile alpha motif domain-containing protein 4B) (SAM domain-containing protein 4B) | 5 | UniProt NCBI |
| YWHAG | 14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed] | 5 | UniProt NCBI |
| HOMEZ | Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper-containing factor) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6730 | 0.0499436884912 | 0.166666666667 | YWHAG | 14-3-3 gamma-CXCR2 complex, unstimulated |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SAMD4B | YWHAG | 0.997 | 0.3265 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM | |
| PLEKHA7 | YWHAG | 0.991 | 0.5056 | bioplex3_HEK293 bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only | |
| CRTC1 | YWHAG | 0.99 | 0.37136 | bioplex3_HEK293 bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| PI4KB | YWHAG | 0.983 | 0.24 | bioplex3_HEK293 bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| YWHAG | HOMEZ | 0.959 | 0.630855106888 |
mutually_exclusive (P27348)
|
bioplex3_HEK293 bioplex3_WMM youn_WMM WMM_only |
| PLEKHA7 | PI4KB | 0.539 | 0.044 | bioplex3_WMM boldt boldt_WMM WMM_only | |
| PI4KB | CRTC1 | 0.539 | 0.112 | bioplex3_WMM boldt boldt_WMM WMM_only | |
| PLEKHA7 | CRTC1 | 0.534 | 0.088 | bioplex3_WMM boldt boldt_WMM WMM_only | |
| PI4KB | SAMD4B | 0.48 | 0.156 | bioplex3_WMM WMM_only boldt_WMM | |
| CRTC1 | SAMD4B | 0.48 | 0.03 | youn () bioplex3_WMM boldt_WMM WMM_only | |
| PLEKHA7 | HOMEZ | 0.385 | 0.066 | bioplex3_WMM WMM_only | |
| CRTC1 | HOMEZ | 0.319 | 0.158 |
mutually_exclusive (P27348)
|
bioplex3_WMM WMM_only |
| PI4KB | HOMEZ | 0.283 | 0.186 | bioplex3_WMM WMM_only | |
| SAMD4B | HOMEZ | 0.153 | 0.084 | bioplex3_WMM youn_WMM WMM_only | |
| PLEKHA7 | SAMD4B | 0.144 | 0.072 | bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
Related Complexes