hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01052.1
Complex Portal: CPX-14440
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZNF598 | E3 ubiquitin-protein ligase ZNF598 (EC 2.3.2.27) (Zinc finger protein 598) | 5 | UniProt NCBI |
| TJP1 | Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-191650 | 0.0249718442456 | 1.0 | TJP1 | Regulation of gap junction activity |
| CORUM:6351 | 0.0499436884912 | 1.0 | TJP1 | PKP1-ZO-1 complex |
| REAC:R-HSA-8935964 | 0.0499436884912 | 1.0 | TJP1 | RUNX1 regulates expression of components of tight junctions |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZNF598 | TJP1 | 0.984 | 0.224 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes