hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01062.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PLEKHH3 | Pleckstrin homology domain-containing family H member 3 (PH domain-containing family H member 3) | 3 | UniProt NCBI |
| PTPRD | Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48) | 5 | UniProt NCBI |
| TGFBR2 | TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3642279 | 0.0249718442457 | 0.5 | TGFBR2 | TGFBR2 MSI Frameshift Mutants in Cancer |
| CORUM:3025 | 0.0249718442457 | 0.5 | TGFBR2 | TGF-beta receptor II-TGF-beta3 complex |
| CORUM:3026 | 0.0249718442457 | 0.5 | TGFBR2 | TGF-beta receptor II-TGF-beta1 complex |
| CORUM:3041 | 0.0249718442457 | 0.5 | TGFBR2 | TGF-beta-receptor type II homodimer complex |
| CORUM:3042 | 0.0249718442457 | 0.5 | TGFBR2 | TGF-beta receptor II-TGF-beta1 complex |
| CORUM:6234 | 0.0249718442457 | 0.5 | TGFBR2 | TGF-betaR2-TGF-beta3 complex |
| WP:WP4904 | 0.0435328773163 | 0.5 | TGFBR2 | LDLRAD4 and what we know about it |
| REAC:R-HSA-3642278 | 0.0499419797295 | 0.5 | TGFBR2 | Loss of Function of TGFBR2 in Cancer |
| REAC:R-HSA-3645790 | 0.0499419797295 | 0.5 | TGFBR2 | TGFBR2 Kinase Domain Mutants in Cancer |
| CORUM:3027 | 0.0499419797295 | 0.5 | TGFBR2 | TGF-beta receptor II-TGF-beta receptor I-TGF-beta1 complex |
| CORUM:3028 | 0.0499419797295 | 0.5 | TGFBR2 | TGF-beta receptor II-TGF-beta receptor I-TGF-beta3 complex |
| CORUM:3031 | 0.0499419797295 | 0.5 | TGFBR2 | Microprocessor complex |
| HP:0004955 | 0.0499436884913 | 0.5 | TGFBR2 | Generalized arterial tortuosity |
| HP:0011934 | 0.0499436884913 | 0.5 | TGFBR2 | Dilatation of mesenteric artery |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PLEKHH3 | TGFBR2 | 0.995 | 0.11 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PTPRD | TGFBR2 | 0.972 | 0.094 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| PTPRD | PLEKHH3 | 0.32 | 0.066 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes