hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01064.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CEP192 | Centrosomal protein of 192 kDa (Cep192) (Cep192/SPD-2) | 5 | UniProt NCBI |
| AURKA | Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Breast tumor-amplified kinase) (Ipl1- and aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase Ayk1) (Serine/threonine-protein kinase aurora-A) | 5 | UniProt NCBI |
| LBHD1 | LBH domain-containing protein 1 | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2361 | 0.00033946652894 | 0.666666666667 | CEP192 AURKA | Gastric cancer network 1 |
| REAC:R-HSA-8854518 | 0.0159472060247 | 0.666666666667 | CEP192 AURKA | AURKA Activation by TPX2 |
| REAC:R-HSA-2565942 | 0.0231174657298 | 0.666666666667 | CEP192 AURKA | Regulation of PLK1 Activity at G2/M Transition |
| CORUM:2581 | 0.0499402709677 | 0.333333333333 | AURKA | RasGAP-AURKA-survivin complex |
| CORUM:6412 | 0.0499402709677 | 0.333333333333 | AURKA | AURKA-HDAC6 cilia-disassembly complex |
| CORUM:6740 | 0.0499402709677 | 0.333333333333 | AURKA | AURKA-INPP5E complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CEP192 | AURKA | 0.994 | 0.326 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| AURKA | LBHD1 | 0.974 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes