hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01084.1
Complex Portal: CPX-16176
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZBTB38 | Zinc finger and BTB domain-containing protein 38 | 5 | UniProt NCBI |
| SIRT1 | NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2592 | 0.0249718442457 | 0.5 | SIRT1 | SIRT1 homotrimer complex |
| WP:WP4186 | 0.0373151717536 | 0.5 | SIRT1 | Somatroph axis GH and its relationship to dietary restriction and aging |
| WP:WP4191 | 0.0373151717536 | 0.5 | SIRT1 | Caloric restriction and aging |
| CORUM:2593 | 0.0499419797295 | 0.5 | SIRT1 | FOXO3-SIRT1 complex, oxidative stress stimulated |
| CORUM:2821 | 0.0499419797295 | 0.5 | SIRT1 | hSIR2-p53 complex |
| CORUM:6846 | 0.0499419797295 | 0.5 | SIRT1 | DBC1-SIRT1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZBTB38 | SIRT1 | 0.998 | 0.191663932584 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| ZBTB38 | huMAP3_01084.1 huMAP3_12000.1 huMAP3_13769.1 |
| SIRT1 | huMAP3_01084.1 huMAP3_12000.1 |