hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01086.1
Complex Portal: CPX-13516
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ALDH5A1 | Succinate-semialdehyde dehydrogenase, mitochondrial (EC 1.2.1.24) (Aldehyde dehydrogenase family 5 member A1) (NAD(+)-dependent succinic semialdehyde dehydrogenase) | 5 | UniProt NCBI |
| MSRB2 | Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.12) (EC 1.8.4.14) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2542 | 0.0248784837172 | 0.5 | MSRB2 | Sulindac metabolic pathway |
| REAC:R-HSA-916853 | 0.0499419797295 | 0.5 | ALDH5A1 | Degradation of GABA |
| HP:0032530 | 0.0499436884913 | 0.5 | ALDH5A1 | Decreased succinic semialdehyde dehydrogenase level |
| HP:0032531 | 0.0499436884913 | 0.5 | ALDH5A1 | Elevated CSF gamma-aminobutyric acid concentration |
| HP:0032532 | 0.0499436884913 | 0.5 | ALDH5A1 | Elevated CSF 4-hydroxybutyric acid concentration |
| HP:0500253 | 0.0499436884913 | 0.5 | ALDH5A1 | Increased level of gamma-aminobutyric acid in urine |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ALDH5A1 | MSRB2 | 0.996 | 0.03 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes