hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01113.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SH3BP1 | SH3 domain-binding protein 1 | 5 | UniProt NCBI |
| ARHGAP44 | Rho GTPase-activating protein 44 (NPC-A-10) (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2) | 5 | UniProt NCBI |
| ARHGAP17 | Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1) | 5 | UniProt NCBI |
| TRIP10 | Cdc42-interacting protein 4 (Protein Felic) (Salt tolerant protein) (hSTP) (Thyroid receptor-interacting protein 10) (TR-interacting protein 10) (TRIP-10) | 5 | UniProt NCBI |
| FNBP1L | Formin-binding protein 1-like (Transducer of Cdc42-dependent actin assembly protein 1) (Toca-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9012999 | 2.25495863817e-06 | 1.0 | ARHGAP17 TRIP10 FNBP1L SH3BP1 ARHGAP44 | RHO GTPase cycle |
| REAC:R-HSA-194315 | 2.37966097899e-05 | 1.0 | ARHGAP17 TRIP10 FNBP1L SH3BP1 ARHGAP44 | Signaling by Rho GTPases |
| REAC:R-HSA-9716542 | 2.65700424583e-05 | 1.0 | ARHGAP17 TRIP10 FNBP1L SH3BP1 ARHGAP44 | Signaling by Rho GTPases, Miro GTPases and RHOBTB3 |
| GO:0035020 | 0.000436807598019 | 0.6 | ARHGAP17 SH3BP1 ARHGAP44 | regulation of Rac protein signal transduction |
| REAC:R-HSA-9013148 | 0.00100303062327 | 0.6 | ARHGAP17 ARHGAP44 FNBP1L | CDC42 GTPase cycle |
| REAC:R-HSA-9013149 | 0.0019808748776 | 0.6 | ARHGAP17 SH3BP1 ARHGAP44 | RAC1 GTPase cycle |
| GO:0016601 | 0.00430818612204 | 0.6 | ARHGAP17 SH3BP1 ARHGAP44 | Rac protein signal transduction |
| GO:0030029 | 0.00536447113949 | 1.0 | ARHGAP17 TRIP10 FNBP1L SH3BP1 ARHGAP44 | actin filament-based process |
| REAC:R-HSA-162582 | 0.00823431736973 | 1.0 | ARHGAP17 TRIP10 FNBP1L SH3BP1 ARHGAP44 | Signal Transduction |
| REAC:R-HSA-9013406 | 0.0208015819243 | 0.4 | ARHGAP17 TRIP10 | RHOQ GTPase cycle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ARHGAP44 | ARHGAP17 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | |
| SH3BP1 | ARHGAP17 | 0.999 | 0.056 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SH3BP1 | ARHGAP44 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ARHGAP44 | FNBP1L | 0.983 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ARHGAP44 | TRIP10 | 0.977 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TRIP10 | FNBP1L | 0.265 | 0.058 | bioplex_WMM bioplex3_WMM fraction |
| SH3BP1 | TRIP10 | 0.183 | 0.17 | bioplex_WMM bioplex3_WMM WMM_only |
| ARHGAP17 | TRIP10 | 0.169 | 0.232 | bioplex_WMM bioplex3_WMM WMM_only |
| SH3BP1 | FNBP1L | 0.143 | 0.046 | bioplex_WMM bioplex3_WMM WMM_only |
| ARHGAP17 | FNBP1L | 0.143 | 0.074 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| SH3BP1 | huMAP3_01113.1 huMAP3_06016.1 huMAP3_12900.1 |
| ARHGAP44 | huMAP3_01113.1 huMAP3_01498.1 huMAP3_07417.1 huMAP3_11985.1 huMAP3_12900.1 |
| ARHGAP17 | huMAP3_01113.1 huMAP3_01443.1 huMAP3_06016.1 huMAP3_12900.1 |
| TRIP10 | huMAP3_01113.1 huMAP3_01498.1 huMAP3_11985.1 huMAP3_14193.1 |
| FNBP1L | huMAP3_01113.1 huMAP3_01498.1 huMAP3_07417.1 huMAP3_11985.1 |