hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01145.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ANKS1B | Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1) | 5 | UniProt NCBI |
| ARHGAP10 | Rho GTPase-activating protein 10 (GTPase regulator associated with focal adhesion kinase 2) (GRAF2) (Graf-related protein 2) (Rho-type GTPase-activating protein 10) | 5 | UniProt NCBI |
| ARHGAP26 | Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (GRAF1) (Oligophrenin-1-like protein) (Rho-type GTPase-activating protein 26) | 5 | UniProt NCBI |
| MICAL1 | [F-actin]-monooxygenase MICAL1 (EC 1.14.13.225) (EC 1.6.3.1) (Molecule interacting with CasL protein 1) (MICAL-1) (NEDD9-interacting protein with calponin homology and LIM domains) | 5 | UniProt NCBI |
| OPHN1 | Oligophrenin-1 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9013148 | 0.00100303062327 | 0.6 | OPHN1 ARHGAP10 ARHGAP26 | CDC42 GTPase cycle |
| REAC:R-HSA-8980692 | 0.00100303062327 | 0.6 | OPHN1 ARHGAP10 ARHGAP26 | RHOA GTPase cycle |
| REAC:R-HSA-9013149 | 0.0019808748776 | 0.6 | OPHN1 ARHGAP10 ARHGAP26 | RAC1 GTPase cycle |
| REAC:R-HSA-9013409 | 0.0208015819243 | 0.4 | OPHN1 ARHGAP26 | RHOJ GTPase cycle |
| REAC:R-HSA-9013406 | 0.0208015819243 | 0.4 | OPHN1 ARHGAP26 | RHOQ GTPase cycle |
| REAC:R-HSA-9013026 | 0.0275944536635 | 0.4 | OPHN1 ARHGAP26 | RHOB GTPase cycle |
| REAC:R-HSA-9012999 | 0.0303172193635 | 0.6 | OPHN1 ARHGAP10 ARHGAP26 | RHO GTPase cycle |
| REAC:R-HSA-9013106 | 0.0313469851718 | 0.4 | OPHN1 ARHGAP26 | RHOC GTPase cycle |
| WP:WP2858 | 0.0379631029161 | 0.4 | ANKS1B ARHGAP10 | Ectoderm differentiation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ARHGAP26 | OPHN1 | 0.999 | 0.172 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ARHGAP10 | ARHGAP26 | 0.999 | 0.164 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM |
| ARHGAP26 | MICAL1 | 0.992 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ANKS1B | ARHGAP26 | 0.965 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ARHGAP10 | OPHN1 | 0.902 | 0.252 | bioplex_WMM bioplex3_WMM WMM_only |
| MICAL1 | OPHN1 | 0.671 | 0.098 | bioplex_WMM bioplex3_WMM WMM_only |
| ARHGAP10 | MICAL1 | 0.622 | 0.084 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes