hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01177.1
Complex Portal: CPX-21554
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SIK2 | Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2) | 5 | UniProt NCBI |
| SIK1 | Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK) | 5 | UniProt NCBI |
| APOBEC3A | DNA dC->dU-editing enzyme APOBEC-3A (A3A) (EC 3.5.4.38) (Phorbolin-1) | 5 | UniProt NCBI |
| MX1 | Interferon-induced GTP-binding protein Mx1 (Interferon-induced protein p78) (IFI-78K) (Interferon-regulated resistance GTP-binding protein MxA) (Myxoma resistance protein 1) (Myxovirus resistance protein 1) [Cleaved into: Interferon-induced GTP-binding protein Mx1, N-terminally processed] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04922 | 0.00318234952896 | 0.666666666667 | SIK1 SIK2 | Glucagon signaling pathway |
| HPA:0500112 | 0.0463845343611 | 1.0 | SIK1 SIK2 APOBEC3A | soft tissue 1; chondrocytes[>=Medium] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SIK1 | APOBEC3A | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SIK1 | MX1 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SIK2 | SIK1 | 0.991 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| APOBEC3A | MX1 | 0.418 | bioplex3_WMM WMM_only | ||
| SIK2 | MX1 | 0.042 | 0.054 | bioplex3_WMM WMM_only | |
| SIK2 | APOBEC3A | 0.042 | bioplex3_WMM WMM_only |
Related Complexes