List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_01184.1

Confidence: Extremely High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
THY1	Thy-1 membrane glycoprotein (CDw90) (Thy-1 antigen) (CD antigen CD90)	5	UniProt   NCBI
PIGS	GPI transamidase component PIG-S (Phosphatidylinositol-glycan biosynthesis class S protein)	5	UniProt   NCBI
GPAA1	Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1)	5	UniProt   NCBI
PIGK	GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K)	5	UniProt   NCBI
PIGU	Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:994	1.91772524101e-12	0.8	PIGS PIGU PIGK GPAA1	GAA1-GPI8-PIGT-PIG-PIGS complex
REAC:R-HSA-162791	1.4947902785e-11	0.8	PIGS PIGU PIGK GPAA1	Attachment of GPI anchor to uPAR
REAC:R-HSA-163125	2.41478117271e-10	1.0	PIGU THY1 PIGK GPAA1 PIGS	Post-translational modification: synthesis of GPI-anchored proteins
GO:0042765	6.57779757665e-10	0.8	PIGS PIGU PIGK GPAA1	GPI-anchor transamidase complex
KEGG:00563	7.63759768495e-10	0.8	PIGS PIGU PIGK GPAA1	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
GO:0016255	1.97323122031e-09	0.8	PIGS PIGU PIGK GPAA1	attachment of GPI anchor to protein
GO:0034235	9.20740386965e-09	0.8	THY1 PIGU PIGK GPAA1	GPI anchor binding
GO:0008303	1.65724193228e-08	0.8	PIGS PIGU PIGK GPAA1	caspase complex
GO:0051861	6.36865069892e-07	0.8	THY1 PIGU PIGK GPAA1	glycolipid binding
GO:0006506	1.396459195e-06	0.8	PIGS PIGU PIGK GPAA1	GPI anchor biosynthetic process
GO:0006505	1.66236029818e-06	0.8	PIGS PIGU PIGK GPAA1	GPI anchor metabolic process
HP:0003155	2.56033703304e-06	0.8	PIGS PIGU PIGK GPAA1	Elevated circulating alkaline phosphatase concentration
HP:0004379	3.99335513945e-06	0.8	PIGS PIGU PIGK GPAA1	Abnormality of alkaline phosphatase level
GO:0009247	5.96974946777e-05	0.8	PIGS PIGU PIGK GPAA1	glycolipid biosynthetic process
GO:0006497	8.87760174517e-05	0.8	PIGS PIGU PIGK GPAA1	protein lipidation
GO:0042158	9.44983107329e-05	0.8	PIGS PIGU PIGK GPAA1	lipoprotein biosynthetic process
GO:1905369	0.000127362420754	0.8	PIGS PIGU PIGK GPAA1	endopeptidase complex
GO:0042157	0.000207211791955	0.8	PIGS PIGU PIGK GPAA1	lipoprotein metabolic process
GO:1903509	0.000240717336774	0.8	PIGS PIGU PIGK GPAA1	liposaccharide metabolic process
GO:0006664	0.000240717336774	0.8	PIGS PIGU PIGK GPAA1	glycolipid metabolic process
GO:1905368	0.000513177059613	0.8	PIGS PIGU PIGK GPAA1	peptidase complex
GO:0140534	0.000625424261446	0.8	PIGS PIGU PIGK GPAA1	endoplasmic reticulum protein-containing complex
GO:0006661	0.000675117158035	0.8	PIGS PIGU PIGK GPAA1	phosphatidylinositol biosynthetic process
REAC:R-HSA-597592	0.000685877408784	1.0	PIGU THY1 PIGK GPAA1 PIGS	Post-translational protein modification
GO:0046467	0.000969335687232	0.8	PIGS PIGU PIGK GPAA1	membrane lipid biosynthetic process
GO:0046488	0.00126658062664	0.8	PIGS PIGU PIGK GPAA1	phosphatidylinositol metabolic process
HP:0001272	0.00164044770812	0.8	PIGS PIGU PIGK GPAA1	Cerebellar atrophy
HP:0003282	0.00230672366147	0.4	PIGS PIGK	Low alkaline phosphatase
GO:0006643	0.00294018150071	0.8	PIGS PIGU PIGK GPAA1	membrane lipid metabolic process
REAC:R-HSA-392499	0.00352060064826	1.0	PIGU THY1 PIGK GPAA1 PIGS	Metabolism of proteins
GO:0046474	0.00407551040215	0.8	PIGS PIGU PIGK GPAA1	glycerophospholipid biosynthetic process
GO:0003923	0.00468200720083	0.4	GPAA1 PIGK	GPI-anchor transamidase activity
HP:0012379	0.00535529637799	0.8	PIGS PIGU PIGK GPAA1	Abnormal circulating enzyme concentration or activity
GO:0035091	0.00685002760202	0.8	THY1 PIGU PIGK GPAA1	phosphatidylinositol binding
GO:0008654	0.00685002760202	0.8	PIGS PIGU PIGK GPAA1	phospholipid biosynthetic process
HP:0034684	0.00749503439327	0.8	PIGS PIGU PIGK GPAA1	Abnormal enzyme concentration or activity
GO:0045017	0.00792260312428	0.8	PIGS PIGU PIGK GPAA1	glycerolipid biosynthetic process
KEGG:01100	0.0139298332568	0.8	PIGS PIGU PIGK GPAA1	Metabolic pathways
GO:0006650	0.0160887636504	0.8	PIGS PIGU PIGK GPAA1	glycerophospholipid metabolic process
GO:0006644	0.0358551890782	0.8	PIGS PIGU PIGK GPAA1	phospholipid metabolic process
GO:0046486	0.0378988106089	0.8	PIGS PIGU PIGK GPAA1	glycerolipid metabolic process
HP:0003189	0.0402186552091	0.4	PIGS PIGU	Long nose
HP:0001317	0.0435465278758	0.8	PIGS PIGU PIGK GPAA1	Abnormal cerebellum morphology
HP:0011282	0.0443303161429	0.8	PIGS PIGU PIGK GPAA1	Abnormal hindbrain morphology
HP:0011283	0.0443303161429	0.8	PIGS PIGU PIGK GPAA1	Abnormal metencephalon morphology



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
PIGS	PIGK	0.999	0.986	hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()     gupta_WMM     boldt_WMM
PIGS	GPAA1	0.999	0.486	hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     boldt     hein ()     gupta_WMM     boldt_WMM
GPAA1	PIGU	0.998	0.07	hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     boldt     gupta_WMM     boldt_WMM
PIGS	PIGU	0.998	0.36	hein_WMM     bioplex_WMM     bioplex3_WMM     boldt     youn_WMM     hein ()     gupta_WMM     boldt_WMM
THY1	GPAA1	0.995	0.078	bioplex3_HEK293     bioplex3_WMM     bioplex3_HCT116     WMM_only
GPAA1	PIGK	0.992	0.386	hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     gupta_WMM     boldt_WMM
PIGK	PIGU	0.992	0.138	hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     boldt_WMM
THY1	PIGU	0.984	0.022	bioplex3_HEK293     bioplex3_WMM     bioplex3_HCT116     WMM_only
THY1	PIGK	0.98	0.082	bioplex3_HEK293     bioplex3_WMM     bioplex3_HCT116     WMM_only
THY1	PIGS	0.979	0.06	bioplex3_HEK293     bioplex3_WMM     bioplex3_HCT116     WMM_only





Related Complexes

Genename	Complexes
THY1	huMAP3_01184.1 huMAP3_04873.1 huMAP3_10360.1 huMAP3_12209.1 huMAP3_12837.1
PIGS	huMAP3_01184.1 huMAP3_04873.1 huMAP3_06250.1 huMAP3_10360.1 huMAP3_12209.1
GPAA1	huMAP3_01184.1 huMAP3_04496.1 huMAP3_10360.1 huMAP3_10536.1 huMAP3_12209.1
PIGK	huMAP3_01184.1 huMAP3_04873.1 huMAP3_06138.1 huMAP3_10360.1
PIGU	huMAP3_01184.1 huMAP3_04475.1 huMAP3_04496.1 huMAP3_06250.1 huMAP3_08648.1 huMAP3_09592.1 huMAP3_10360.1