hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01185.1
Complex Portal: CPX-22641
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| EXD2 | Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) | 5 | UniProt NCBI |
| TMEM151A | Transmembrane protein 151A | 5 | UniProt NCBI |
| SLC31A1 | High affinity copper uptake protein 1 (Copper transporter 1) (hCTR1) (Solute carrier family 31 member 1) [Cleaved into: Truncated CTR1 form] | 5 | UniProt NCBI |
| MEAK7 | MTOR-associated protein MEAK7 (MEAK7) (MTOR associated protein, eak-7 homolog) (TBC/LysM-associated domain-containing protein 1) (TLD domain-containing protein 1) | 5 | UniProt NCBI |
| CERK | Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4) | 5 | UniProt NCBI |
| SLC31A2 | Protein SLC31A2 (Copper transporter 2) (hCTR2) (Solute carrier family 31 member 2) | 5 | UniProt NCBI |
| C2orf72 | Uncharacterized protein C2orf72 | 1 | UniProt NCBI |
| DTWD1 | tRNA-uridine aminocarboxypropyltransferase 1 (EC 2.5.1.25) (DTW domain-containing protein 1) | 4 | UniProt NCBI |
| ACP2 | Lysosomal acid phosphatase (LAP) (EC 3.1.3.2) | 5 | UniProt NCBI |
| INPP4B | Inositol polyphosphate 4-phosphatase type II (Type II inositol 3,4-bisphosphate 4-phosphatase) (EC 3.1.3.66) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3286 | 0.0287089830042 | 0.222222222222 | SLC31A1 SLC31A2 | Copper homeostasis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SLC31A1 | C2orf72 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SLC31A1 | SLC31A2 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TMEM151A | SLC31A1 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SLC31A1 | DTWD1 | 0.997 | 0.124 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| EXD2 | SLC31A1 | 0.995 | 0.156 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SLC31A1 | ACP2 | 0.988 | 0.126185074627 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| INPP4B | SLC31A1 | 0.979 | 0.024 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SLC31A1 | MEAK7 | 0.966 | 0.06 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SLC31A1 | CERK | 0.965 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SLC31A2 | ACP2 | 0.958 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| C2orf72 | DTWD1 | 0.946 | bioplex3_WMM WMM_only | ||
| TMEM151A | C2orf72 | 0.902 | bioplex3_WMM WMM_only | ||
| TMEM151A | DTWD1 | 0.902 | bioplex3_WMM WMM_only | ||
| INPP4B | TMEM151A | 0.902 | bioplex3_WMM WMM_only | ||
| INPP4B | C2orf72 | 0.902 | bioplex3_WMM WMM_only | ||
| MEAK7 | C2orf72 | 0.882 | bioplex3_WMM WMM_only | ||
| TMEM151A | MEAK7 | 0.882 | bioplex3_WMM WMM_only | ||
| CERK | DTWD1 | 0.773 | bioplex3_WMM WMM_only | ||
| CERK | C2orf72 | 0.757 | bioplex3_WMM WMM_only | ||
| TMEM151A | CERK | 0.715 | bioplex3_WMM WMM_only | ||
| INPP4B | CERK | 0.675 | bioplex3_WMM WMM_only | ||
| MEAK7 | CERK | 0.611 | bioplex3_WMM WMM_only | ||
| EXD2 | C2orf72 | 0.496 | bioplex3_WMM WMM_only | ||
| INPP4B | DTWD1 | 0.468 | 0.058 | bioplex3_WMM WMM_only | |
| EXD2 | CERK | 0.468 | bioplex3_WMM WMM_only | ||
| INPP4B | MEAK7 | 0.435 | 0.03 | bioplex3_WMM WMM_only | |
| TMEM151A | ACP2 | 0.401 | bioplex3_WMM WMM_only | ||
| C2orf72 | ACP2 | 0.391 | bioplex3_WMM WMM_only | ||
| EXD2 | TMEM151A | 0.376 | bioplex3_WMM WMM_only | ||
| MEAK7 | DTWD1 | 0.311 | 0.072 | bioplex3_WMM WMM_only | |
| EXD2 | DTWD1 | 0.264 | 0.064 | bioplex3_WMM WMM_only | |
| INPP4B | EXD2 | 0.243 | 0.018 | bioplex3_WMM WMM_only | |
| CERK | ACP2 | 0.201 | bioplex_WMM bioplex3_WMM WMM_only | ||
| INPP4B | ACP2 | 0.183 | 0.014 | bioplex3_WMM WMM_only | |
| EXD2 | ACP2 | 0.127 | 0.132 | bioplex_WMM bioplex3_WMM WMM_only | |
| EXD2 | MEAK7 | 0.104 | 0.052 | bioplex3_WMM WMM_only | |
| DTWD1 | ACP2 | 0.103 | 0.044 | bioplex3_WMM WMM_only | |
| MEAK7 | ACP2 | 0.089 | 0.01 | bioplex3_WMM WMM_only |
Related Complexes