hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01203.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AQR | RNA helicase aquarius (EC 3.6.4.13) (Intron-binding protein of 160 kDa) (IBP160) | 5 | UniProt NCBI |
| KIAA1143 | Uncharacterized protein KIAA1143 | 2 | UniProt NCBI |
| BUD31 | Protein BUD31 homolog (Protein EDG-2) (Protein G10 homolog) | 5 | UniProt NCBI |
| CDC40 | Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3) (PRP17 homolog) (hPRP17) | 5 | UniProt NCBI |
| CRNKL1 | Crooked neck-like protein 1 (Crooked neck homolog) (hCrn) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03040 | 1.22968992878e-06 | 0.8 | CRNKL1 AQR CDC40 BUD31 | Spliceosome |
| GO:0071007 | 3.60035554513e-06 | 0.8 | CRNKL1 AQR CDC40 BUD31 | U2-type catalytic step 2 spliceosome |
| CORUM:351 | 5.34752441749e-06 | 0.8 | CRNKL1 AQR CDC40 BUD31 | Spliceosome |
| REAC:R-HSA-72163 | 2.78873163091e-05 | 0.8 | CRNKL1 AQR CDC40 BUD31 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 3.19999178813e-05 | 0.8 | CRNKL1 AQR CDC40 BUD31 | mRNA Splicing |
| REAC:R-HSA-72203 | 9.66841881558e-05 | 0.8 | CRNKL1 AQR CDC40 BUD31 | Processing of Capped Intron-Containing Pre-mRNA |
| CORUM:1181 | 0.000203436600886 | 0.6 | CRNKL1 AQR CDC40 | C complex spliceosome |
| GO:0071013 | 0.00029151492518 | 0.8 | CRNKL1 AQR CDC40 BUD31 | catalytic step 2 spliceosome |
| GO:0005684 | 0.000319733015871 | 0.8 | CRNKL1 AQR CDC40 BUD31 | U2-type spliceosomal complex |
| REAC:R-HSA-8953854 | 0.00371793814615 | 0.8 | CRNKL1 AQR CDC40 BUD31 | Metabolism of RNA |
| GO:0005681 | 0.00437843642246 | 0.8 | CRNKL1 AQR CDC40 BUD31 | spliceosomal complex |
| GO:0000377 | 0.0264444778619 | 0.8 | CRNKL1 AQR CDC40 BUD31 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| GO:0000398 | 0.0264444778619 | 0.8 | CRNKL1 AQR CDC40 BUD31 | mRNA splicing, via spliceosome |
| GO:0000375 | 0.0280745884658 | 0.8 | CRNKL1 AQR CDC40 BUD31 | RNA splicing, via transesterification reactions |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| AQR | CDC40 | 1.0 | 0.608 | hein_WMM bioplex_WMM Guru bioplex3_WMM youn_WMM fraction treiber_WMM |
| AQR | CRNKL1 | 1.0 | 0.724 | hein_WMM bioplex_WMM Guru bioplex3_WMM youn_WMM hein () Malo gupta_WMM fraction treiber_WMM |
| CDC40 | CRNKL1 | 1.0 | 0.682 | hein_WMM bioplex_WMM Guru bioplex3_WMM youn_WMM hein () fraction treiber_WMM |
| BUD31 | CDC40 | 0.999 | 0.446 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| AQR | BUD31 | 0.999 | 0.342 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| BUD31 | CRNKL1 | 0.998 | 0.43 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| AQR | KIAA1143 | 0.991 | 0.068 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| KIAA1143 | CRNKL1 | 0.969 | 0.06 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| KIAA1143 | BUD31 | 0.963 | 0.086 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| KIAA1143 | CDC40 | 0.957 | 0.09 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
Related Complexes