hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01242.1
Complex Portal: CPX-22785
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CTNNA3 | Catenin alpha-3 (Alpha T-catenin) (Cadherin-associated protein) | 5 | UniProt NCBI |
| CDH3 | Cadherin-3 (Placental cadherin) (P-cadherin) | 5 | UniProt NCBI |
| CDH4 | Cadherin-4 (Retinal cadherin) (R-CAD) (R-cadherin) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5087 | 0.000659719901928 | 1.0 | CDH3 CTNNA3 CDH4 | Pleural mesothelioma |
| REAC:R-HSA-418990 | 0.00257431960226 | 0.666666666667 | CDH3 CDH4 | Adherens junctions interactions |
| WP:WP4540 | 0.00374811209074 | 0.666666666667 | CDH3 CDH4 | Hippo signaling regulation pathways |
| KEGG:04514 | 0.00406958776216 | 0.666666666667 | CDH3 CDH4 | Cell adhesion molecules |
| WP:WP4541 | 0.00514316015145 | 0.666666666667 | CDH3 CDH4 | Hippo Merlin signaling dysregulation |
| REAC:R-HSA-421270 | 0.00673703034894 | 0.666666666667 | CDH3 CDH4 | Cell-cell junction organization |
| REAC:R-HSA-446728 | 0.017372320015 | 0.666666666667 | CDH3 CDH4 | Cell junction organization |
| REAC:R-HSA-1500931 | 0.0356523169758 | 0.666666666667 | CDH3 CDH4 | Cell-Cell communication |
| GO:0005912 | 0.0360123345897 | 1.0 | CDH3 CTNNA3 CDH4 | adherens junction |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CTNNA3 | CDH4 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CDH3 | CTNNA3 | 0.992 |
mutually_exclusive (P35222)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CDH3 | CDH4 | 0.188 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes