hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01266.1
Complex Portal: CPX-20517
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IRAK1 | Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1) | 5 | UniProt NCBI |
| GART | Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3926 | 0.0272601008896 | 1.0 | IRAK1 | ApoE and miR 146 in inflammation and atherosclerosis |
| WP:WP3656 | 0.0454335014827 | 1.0 | IRAK1 | Interleukin 1 induced activation of NF kB |
| CORUM:1944 | 0.0499436884912 | 1.0 | IRAK1 | IRAK1-IRAK2 complex |
| CORUM:1945 | 0.0499436884912 | 1.0 | IRAK1 | IRAK1-IRAK3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GART | IRAK1 | 0.979 | 0.136 | bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only |
Related Complexes