hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01288.1
Complex Portal: CPX-13156
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SDE2 | Splicing regulator SDE2 (Replication stress response regulator SDE2) | 5 | UniProt NCBI |
| PYM1 | Partner of Y14 and mago (PYM homolog 1 exon junction complex-associated factor) (Protein wibg homolog) | 5 | UniProt NCBI |
| RBM8A | RNA-binding protein 8A (Binder of OVCA1-1) (BOV-1) (RNA-binding motif protein 8A) (RNA-binding protein Y14) (Ribonucleoprotein RBM8A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:755 | 3.41705576683e-05 | 0.666666666667 | RBM8A PYM1 | Exon junction complex (EIF4A3, MLN51, UPF3B, MAGOH, Y14, PYM) |
| KEGG:03015 | 0.00311331063035 | 0.666666666667 | RBM8A PYM1 | mRNA surveillance pathway |
| KEGG:03013 | 0.00383761092368 | 0.666666666667 | RBM8A PYM1 | Nucleocytoplasmic transport |
| HPA:0330223 | 0.0265048582464 | 1.0 | SDE2 PYM1 RBM8A | oral mucosa; squamous epithelial cells[High] |
| CORUM:763 | 0.0499402709677 | 0.333333333333 | RBM8A | Y14-Magoh complex |
| CORUM:773 | 0.0499402709677 | 0.333333333333 | RBM8A | Y14-Magoh complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RBM8A | PYM1 | 0.996 | 0.096 |
mutually_exclusive (Q96A72)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM |
| RBM8A | SDE2 | 0.991 | 0.202 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM | |
| SDE2 | PYM1 | 0.032 | 0.092 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes