hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01290.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CCDC93 | Coiled-coil domain-containing protein 93 | 5 | UniProt NCBI |
| COMMD9 | COMM domain-containing protein 9 | 5 | UniProt NCBI |
| COMMD7 | COMM domain-containing protein 7 | 5 | UniProt NCBI |
| COMMD2 | COMM domain-containing protein 2 | 4 | UniProt NCBI |
| VPS29 | Vacuolar protein sorting-associated protein 29 (hVPS29) (PEP11 homolog) (Vesicle protein sorting 29) | 5 | UniProt NCBI |
| COMMD10 | COMM domain-containing protein 10 | 5 | UniProt NCBI |
| COMMD4 | COMM domain-containing protein 4 | 5 | UniProt NCBI |
| DENND10 | DENN domain-containing protein 10 (Protein FAM45A) | 5 | UniProt NCBI |
| TGIF1 | Homeobox protein TGIF1 (5'-TG-3'-interacting factor 1) | 5 | UniProt NCBI |
| VPS26C | Vacuolar protein sorting-associated protein 26C (Down syndrome critical region protein 3) (Down syndrome critical region protein A) | 5 | UniProt NCBI |
| COMMD8 | COMM domain-containing protein 8 | 4 | UniProt NCBI |
| CCDC22 | Coiled-coil domain-containing protein 22 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6645 | 7.51130479879e-22 | 0.666666666667 | COMMD7 COMMD8 CCDC22 COMMD4 CCDC93 COMMD2 COMMD10 COMMD9 | CCC complex |
| CORUM:6639 | 3.75382367243e-21 | 0.666666666667 | COMMD7 COMMD8 CCDC22 COMMD4 CCDC93 COMMD2 COMMD10 COMMD9 | CCC-Wash (WASH1, FAM21C) complex |
| REAC:R-HSA-8951664 | 3.76464599268e-08 | 0.583333333333 | COMMD7 COMMD8 CCDC22 COMMD4 COMMD9 COMMD2 COMMD10 | Neddylation |
| CORUM:6658 | 0.000112726824524 | 0.166666666667 | COMMD8 CCDC22 | CCDC22-COMMD8-CUL1 complex |
| CORUM:6659 | 0.000112726824524 | 0.166666666667 | COMMD8 CCDC22 | Ubiquitin E3 ligase (CCDC22, COMMD8, CUL3) |
| CORUM:7132 | 0.000112726824524 | 0.166666666667 | CCDC93 CCDC22 | CCDC22-CCDC93-C16orf62 complex |
| CORUM:7131 | 0.000225350794349 | 0.166666666667 | CCDC93 CCDC22 | COMMD1-CCDC22-CCDC93-C16orf62 complex |
| CORUM:7135 | 0.000375413311943 | 0.166666666667 | CCDC93 CCDC22 | CCDC22-CCDC93-C16orf62-FAM21-WASH1 complex |
| REAC:R-HSA-597592 | 0.00438232273266 | 0.583333333333 | COMMD7 COMMD8 CCDC22 COMMD4 COMMD9 COMMD2 COMMD10 | Post-translational protein modification |
| GO:0032456 | 0.0153454201845 | 0.333333333333 | VPS26C CCDC93 CCDC22 VPS29 | endocytic recycling |
| REAC:R-HSA-392499 | 0.037111324721 | 0.583333333333 | COMMD7 COMMD8 CCDC22 COMMD4 COMMD9 COMMD2 COMMD10 | Metabolism of proteins |
| GO:0016197 | 0.0448077185615 | 0.416666666667 | DENND10 VPS26C CCDC93 CCDC22 VPS29 | endosomal transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| VPS26C | CCDC22 | 1.0 | 0.296 |
| CCDC93 | VPS26C | 1.0 | 0.196 |
| CCDC93 | COMMD2 | 1.0 | 0.348 |
| CCDC93 | CCDC22 | 1.0 | 0.732 |
| COMMD4 | CCDC22 | 1.0 | 0.166 |
| COMMD10 | CCDC22 | 1.0 | 0.804 |
| DENND10 | CCDC22 | 1.0 | 0.138 |
| CCDC93 | COMMD10 | 1.0 | 0.792 |
| DENND10 | VPS26C | 1.0 | 0.072 |
| COMMD4 | VPS26C | 1.0 | 0.036 |
| COMMD2 | VPS26C | 1.0 | 0.08 |
| COMMD7 | CCDC22 | 1.0 | 0.514 |
| COMMD2 | CCDC22 | 1.0 | 0.31 |
| CCDC93 | DENND10 | 1.0 | 0.446 |
| CCDC93 | COMMD7 | 1.0 | 0.376 |
| COMMD9 | CCDC22 | 1.0 | 0.508 |
| COMMD2 | COMMD8 | 1.0 | 0.456 |
| VPS29 | COMMD10 | 1.0 | 0.188 |
| VPS29 | COMMD8 | 1.0 | 0.122 |
| COMMD8 | CCDC22 | 1.0 | 0.122 |
| VPS29 | COMMD2 | 1.0 | 0.206 |
| COMMD2 | COMMD4 | 1.0 | 0.45 |
| VPS29 | COMMD4 | 1.0 | 0.088 |
| CCDC93 | COMMD9 | 1.0 | 0.414 |
| COMMD7 | COMMD2 | 1.0 | 0.206 |
| COMMD4 | COMMD8 | 0.999 | 0.394 |
| COMMD10 | COMMD8 | 0.999 | 0.338 |
| COMMD10 | VPS26C | 0.999 | 0.43 |
| VPS29 | CCDC22 | 0.999 | 0.354 |
| COMMD2 | DENND10 | 0.999 | 0.188 |
| CCDC93 | COMMD4 | 0.999 | 0.256 |
| COMMD4 | DENND10 | 0.999 | 0.14 |
| COMMD10 | DENND10 | 0.999 | 0.104 |
| DENND10 | COMMD8 | 0.999 | 0.382 |
| CCDC93 | COMMD8 | 0.999 | 0.116 |
| VPS29 | VPS26C | 0.999 | 0.146 |
| COMMD10 | COMMD4 | 0.999 | 0.65 |
| COMMD9 | COMMD8 | 0.999 | 0.59 |
| VPS29 | COMMD9 | 0.999 | 0.328 |
| VPS29 | DENND10 | 0.999 | 0.244 |
| COMMD2 | COMMD10 | 0.999 | 0.658 |
| COMMD9 | COMMD10 | 0.999 | 0.93 |
| VPS29 | CCDC93 | 0.999 | 0.274 |
| COMMD9 | VPS26C | 0.999 | 0.266 |
| COMMD9 | COMMD7 | 0.999 | 0.724 |
| COMMD7 | VPS26C | 0.999 | 0.24 |
| COMMD7 | COMMD10 | 0.999 | 0.444 |
| VPS29 | COMMD7 | 0.999 | 0.328 |
| VPS26C | COMMD8 | 0.998 | 0.032 |
| COMMD9 | DENND10 | 0.998 | 0.092 |
| COMMD7 | COMMD4 | 0.998 | 0.408 |
| COMMD9 | COMMD2 | 0.998 | 0.398 |
| COMMD7 | DENND10 | 0.998 | 0.208 |
| COMMD7 | COMMD8 | 0.998 | 0.414 |
| COMMD9 | COMMD4 | 0.998 | 0.486 |
| TGIF1 | COMMD8 | 0.991 | 0.084 |
| COMMD2 | TGIF1 | 0.99 | 0.09 |
| COMMD4 | TGIF1 | 0.988 | 0.062 |
| VPS29 | TGIF1 | 0.634 | 0.06 |
| TGIF1 | CCDC22 | 0.634 | 0.05 |
| DENND10 | TGIF1 | 0.634 | 0.088 |
| COMMD9 | TGIF1 | 0.634 | 0.136 |
| TGIF1 | VPS26C | 0.634 | 0.034 |
| COMMD10 | TGIF1 | 0.634 | 0.112 |
| CCDC93 | TGIF1 | 0.634 | 0.138 |
| COMMD7 | TGIF1 | 0.634 | 0.204 |
Related Complexes
| Genename | Complexes |
|---|---|
| CCDC93 | huMAP3_01290.1 huMAP3_07032.1 huMAP3_14444.1 |
| COMMD9 | huMAP3_01290.1 huMAP3_07032.1 huMAP3_14444.1 |
| COMMD7 | huMAP3_01290.1 huMAP3_07032.1 huMAP3_14444.1 |
| COMMD2 | huMAP3_01290.1 huMAP3_07032.1 huMAP3_14444.1 |
| VPS29 | huMAP3_01277.1 huMAP3_01290.1 huMAP3_07032.1 huMAP3_13244.1 huMAP3_14444.1 |
| COMMD10 | huMAP3_01290.1 huMAP3_07032.1 huMAP3_14444.1 |
| COMMD4 | huMAP3_01290.1 huMAP3_07032.1 huMAP3_14444.1 |
| DENND10 | huMAP3_01290.1 huMAP3_07032.1 huMAP3_11422.1 huMAP3_14444.1 |
| TGIF1 | huMAP3_01290.1 huMAP3_07032.1 huMAP3_14444.1 |
| VPS26C | huMAP3_01290.1 huMAP3_07032.1 huMAP3_14444.1 |
| COMMD8 | huMAP3_01290.1 huMAP3_07032.1 huMAP3_14444.1 |
| CCDC22 | huMAP3_01290.1 huMAP3_07032.1 huMAP3_14444.1 |