hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01293.1
Complex Portal: CPX-11747
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RELL1 | RELT-like protein 1 | 5 | UniProt NCBI |
| STK39 | STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39) | 5 | UniProt NCBI |
| RELT | Tumor necrosis factor receptor superfamily member 19L (Receptor expressed in lymphoid tissues) | 5 | UniProt NCBI |
| OXSR1 | Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003096 | 0.0280843539964 | 0.5 | OXSR1 STK39 | renal sodium ion transport |
| GO:0038146 | 0.0280843539964 | 0.5 | OXSR1 STK39 | chemokine (C-X-C motif) ligand 12 signaling pathway |
| GO:0070294 | 0.0280843539964 | 0.5 | OXSR1 STK39 | renal sodium ion absorption |
| KEGG:04060 | 0.0475663770677 | 0.5 | RELL1 RELT | Cytokine-cytokine receptor interaction |
| CORUM:1121 | 0.049938562206 | 0.25 | OXSR1 | WNK1-OSR1 complex |
| CORUM:1123 | 0.049938562206 | 0.25 | STK39 | WNK1-SPAK complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| STK39 | RELT | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| RELT | OXSR1 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| RELL1 | OXSR1 | 0.992 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| STK39 | OXSR1 | 0.979 | 0.198 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| RELL1 | STK39 | 0.966 | 0.05 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes