hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_01297.1

Confidence: Extremely High

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Genename	Protein Name	Uniprot Annotation Score	Links
AP5M1	AP-5 complex subunit mu-1 (Adaptor-related protein complex 5 subunit mu-1) (Mu5) (Mu-2-related death-inducing protein) (MuD) (Putative HIV-1 infection-related protein)	5	UniProt NCBI
AP5S1	AP-5 complex subunit sigma-1 (Adaptor-related protein complex 5 sigma subunit) (Sigma5)	5	UniProt NCBI
AP5Z1	AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5)	5	UniProt NCBI
SPG11	Spatacsin (Colorectal carcinoma-associated protein) (Spastic paraplegia 11 protein)	5	UniProt NCBI
ZFYVE26	Zinc finger FYVE domain-containing protein 26 (FYVE domain-containing centrosomal protein) (FYVE-CENT) (Spastizin)	5	UniProt NCBI

Showing 1 to 5 of 5 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:6602	1.57511210607e-16	1.0	AP5S1 SPG11 AP5M1 AP5Z1 ZFYVE26	AP5-SPG11-SPG15 complex
CORUM:6626	1.12081835382e-08	0.6	AP5S1 AP5Z1 AP5M1	AP5 adaptor complex
GO:0044599	3.84440695359e-06	0.6	AP5S1 AP5Z1 AP5M1	AP-5 adaptor complex
HP:0002839	3.02160410061e-05	0.6	ZFYVE26 AP5Z1 SPG11	Urinary bladder sphincter dysfunction
HP:0002064	0.000598637712806	0.6	ZFYVE26 AP5Z1 SPG11	Spastic gait
HP:0030890	0.000685212767946	0.6	ZFYVE26 AP5Z1 SPG11	Hyperintensity of cerebral white matter on MRI
HP:0001258	0.0022378814793	0.6	ZFYVE26 AP5Z1 SPG11	Spastic paraplegia
HP:0000020	0.00403288766139	0.6	ZFYVE26 AP5Z1 SPG11	Urinary incontinence
HP:0010550	0.00443745887352	0.6	ZFYVE26 AP5Z1 SPG11	Paraplegia
GO:0030119	0.00627040828674	0.6	AP5S1 AP5Z1 AP5M1	AP-type membrane coat adaptor complex

Showing 1 to 10 of 20 entries

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Protein 1	Protein 2	Score	ProteomeHD	Evidence
AP5S1	ZFYVE26	0.999	0.148	bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
AP5Z1	SPG11	0.999	0.15	bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
AP5S1	AP5Z1	0.998	0.334	bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
AP5S1	SPG11	0.998	0.112	bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
SPG11	AP5M1	0.998	0.202	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
AP5S1	AP5M1	0.998	0.232	bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
ZFYVE26	AP5M1	0.811	0.174	bioplex3_WMM WMM_only
AP5Z1	AP5M1	0.804	0.102	bioplex3_WMM WMM_only
ZFYVE26	AP5Z1	0.727	0.214	bioplex3_WMM WMM_only
ZFYVE26	SPG11	0.722	0.198	bioplex3_WMM WMM_only

Showing 1 to 10 of 10 entries

Related Complexes

Genename	Complexes
AP5S1	huMAP3_01297.1 huMAP3_09124.1 huMAP3_14796.1
ZFYVE26	huMAP3_01297.1 huMAP3_09124.1 huMAP3_14796.1
AP5Z1	huMAP3_01297.1 huMAP3_09124.1 huMAP3_14796.1
SPG11	huMAP3_01297.1 huMAP3_09124.1 huMAP3_14796.1
AP5M1	huMAP3_01297.1 huMAP3_09124.1 huMAP3_12854.1 huMAP3_14796.1