hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01307.1
Complex Portal: CPX-23881
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TLN2 | Talin-2 | 5 | UniProt NCBI |
| KANK4 | KN motif and ankyrin repeat domain-containing protein 4 (Ankyrin repeat domain-containing protein 38) | 5 | UniProt NCBI |
| TLN1 | Talin-1 | 5 | UniProt NCBI |
| RGCC | Regulator of cell cycle RGCC (Response gene to complement 32 protein) (RGC-32) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04611 | 0.0118173906169 | 0.5 | TLN2 TLN1 | Platelet activation |
| CORUM:2378 | 0.0249718442456 | 0.25 | TLN1 | ITGA2b-ITGB3-TLN1 complex |
| KEGG:04015 | 0.0338381888916 | 0.5 | TLN2 TLN1 | Rap1 signaling pathway |
| KEGG:04510 | 0.03673756538 | 0.5 | TLN2 TLN1 | Focal adhesion |
| WP:WP306 | 0.0374055211141 | 0.5 | TLN2 TLN1 | Focal adhesion |
| KEGG:05166 | 0.0480473295333 | 0.5 | TLN2 TLN1 | Human T-cell leukemia virus 1 infection |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TLN2 | KANK4 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| TLN2 | RGCC | 0.995 | 0.098 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| KANK4 | TLN1 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| TLN1 | RGCC | 0.978 | 0.296 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TLN2 | TLN1 | 0.959 | 0.108 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only boldt_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| TLN2 | huMAP3_01307.1 huMAP3_11545.1 huMAP3_12291.1 |
| KANK4 | huMAP3_01307.1 huMAP3_12177.1 huMAP3_13223.1 |
| TLN1 | huMAP3_01307.1 huMAP3_09166.1 huMAP3_10349.1 huMAP3_10995.1 huMAP3_14982.1 |
| RGCC | huMAP3_01307.1 huMAP3_11545.1 huMAP3_11742.1 huMAP3_12291.1 |