hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01312.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GPALPP1 | GPALPP motifs-containing protein 1 (Lipopolysaccharide-specific response protein 7) | 3 | UniProt NCBI |
| CCDC9 | Coiled-coil domain-containing protein 9 | 4 | UniProt NCBI |
| NKTR | NK-tumor recognition protein (NK-TR protein) (Natural-killer cells cyclophilin-related protein) (Peptidyl-prolyl cis-trans isomerase NKTR) (PPIase) (EC 5.2.1.8) (Rotamase) | 5 | UniProt NCBI |
| MAGOHB | Protein mago nashi homolog 2 | 5 | UniProt NCBI |
| EIF4A3 | Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed] | 5 | UniProt NCBI |
| PNN | Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0035145 | 1.90892139407e-06 | 0.666666666667 | CCDC9 PNN MAGOHB EIF4A3 | exon-exon junction complex |
| KEGG:03015 | 0.000238502370467 | 0.5 | EIF4A3 MAGOHB PNN | mRNA surveillance pathway |
| KEGG:03013 | 0.000326665904496 | 0.5 | EIF4A3 MAGOHB PNN | Nucleocytoplasmic transport |
| REAC:R-HSA-72163 | 0.00913908174037 | 0.5 | EIF4A3 MAGOHB PNN | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.0101216651073 | 0.5 | EIF4A3 MAGOHB PNN | mRNA Splicing |
| REAC:R-HSA-72203 | 0.0229811698012 | 0.5 | EIF4A3 MAGOHB PNN | Processing of Capped Intron-Containing Pre-mRNA |
| REAC:R-HSA-72187 | 0.0379731829042 | 0.333333333333 | EIF4A3 MAGOHB | mRNA 3'-end processing |
| CORUM:1181 | 0.0493179573456 | 0.333333333333 | EIF4A3 PNN | C complex spliceosome |
| REAC:R-HSA-73856 | 0.0498675109087 | 0.333333333333 | EIF4A3 MAGOHB | RNA Polymerase II Transcription Termination |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CCDC9 | EIF4A3 | 1.0 | 0.1 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () |
| PNN | CCDC9 | 0.999 | 0.158 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () |
| PNN | EIF4A3 | 0.996 | 0.896 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM |
| NKTR | CCDC9 | 0.996 | 0.062 | hein_WMM bioplex_WMM bioplex3_WMM hein () |
| CCDC9 | MAGOHB | 0.99 | 0.058 | hein_WMM bioplex3_WMM hein () |
| NKTR | PNN | 0.989 | 0.29 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| NKTR | EIF4A3 | 0.985 | 0.292 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| GPALPP1 | CCDC9 | 0.974 | 0.136 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| PNN | MAGOHB | 0.97 | 0.766 | hein_WMM bioplex3_WMM WMM_only |
| PNN | GPALPP1 | 0.937 | 0.328 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM |
| MAGOHB | EIF4A3 | 0.869 | 0.84 | hein_WMM bioplex3_WMM gupta_WMM WMM_only |
| NKTR | GPALPP1 | 0.668 | 0.126 | bioplex_WMM bioplex3_WMM WMM_only |
| GPALPP1 | EIF4A3 | 0.357 | 0.136 | hein_WMM youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| NKTR | MAGOHB | 0.232 | 0.15 | hein_WMM WMM_only |
Related Complexes