hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01319.1
Complex Portal: CPX-19043
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MCOLN1 | Mucolipin-1 (ML1) (MG-2) (Mucolipidin) (Transient receptor potential channel mucolipin 1) (TRPML1) | 5 | UniProt NCBI |
| LY6D | Lymphocyte antigen 6D (Ly-6D) (E48 antigen) | 5 | UniProt NCBI |
| MCOLN2 | Mucolipin-2 (Transient receptor potential channel mucolipin 2) (TRPML2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3295583 | 0.000926675585137 | 0.666666666667 | MCOLN1 MCOLN2 | TRP channels |
| KEGG:04020 | 0.0111390641405 | 0.666666666667 | MCOLN1 MCOLN2 | Calcium signaling pathway |
| GO:0072345 | 0.0140440992017 | 0.666666666667 | MCOLN1 MCOLN2 | NAADP-sensitive calcium-release channel activity |
| REAC:R-HSA-2672351 | 0.0141416283812 | 0.666666666667 | MCOLN1 MCOLN2 | Stimuli-sensing channels |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MCOLN1 | LY6D | 0.98 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MCOLN1 | MCOLN2 | 0.971 |
mutually_exclusive (Q8TDD5)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| LY6D | MCOLN2 | 0.971 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| MCOLN1 | huMAP3_01319.1 huMAP3_10268.1 huMAP3_11767.1 huMAP3_13049.1 |
| LY6D | huMAP3_01319.1 huMAP3_10268.1 huMAP3_11767.1 huMAP3_12044.1 huMAP3_13049.1 |
| MCOLN2 | huMAP3_01319.1 huMAP3_10268.1 huMAP3_11767.1 huMAP3_13049.1 |