hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01335.1
Complex Portal: CPX-17891
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DNAJA1 | DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2) | 5 | UniProt NCBI |
| AHR | Aryl hydrocarbon receptor (Ah receptor) (AhR) (Class E basic helix-loop-helix protein 76) (bHLHe76) | 5 | UniProt NCBI |
| PLD2 | Phospholipase D2 (PLD 2) (hPLD2) (EC 3.1.4.4) (Choline phosphatase 2) (PLD1C) (Phosphatidylcholine-hydrolyzing phospholipase D2) | 5 | UniProt NCBI |
| RADX | RPA-related protein RADX (RPA-related and RAD51-antagonist, X-chromosome) | 5 | UniProt NCBI |
| TANGO6 | Transport and Golgi organization protein 6 homolog (Transmembrane and coiled-coil domain-containing protein 7) | 3 | UniProt NCBI |
| DNAJA2 | DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14) | 5 | UniProt NCBI |
| SQOR | Sulfide:quinone oxidoreductase, mitochondrial (SQOR) (EC 1.8.5.8) (Sulfide dehydrogenase-like) (Sulfide quinone oxidoreductase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3371497 | 0.0499595563988 | 0.285714285714 | DNAJA1 DNAJA2 | HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DNAJA2 | DNAJA1 | 1.0 | 0.382 |
mutually_exclusive (Q14249)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM |
| DNAJA2 | AHR | 0.989 | 0.0446133333333 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| DNAJA2 | RADX | 0.979 | 0.132 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only | |
| DNAJA2 | TANGO6 | 0.974 | 0.118 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only | |
| DNAJA2 | PLD2 | 0.962 | 0.092 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only | |
| DNAJA2 | SQOR | 0.951 | 0.04 | hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 treiber_WMM WMM_only | |
| DNAJA1 | PLD2 | 0.92 | 0.096 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | |
| DNAJA1 | RADX | 0.914 | 0.07 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM | |
| TANGO6 | PLD2 | 0.724 | 0.218 | bioplex_WMM bioplex3_WMM WMM_only | |
| PLD2 | RADX | 0.689 | 0.136 | bioplex_WMM bioplex3_WMM WMM_only | |
| DNAJA1 | SQOR | 0.593 | 0.082 | hein_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM WMM_only | |
| AHR | PLD2 | 0.591 | 0.136 | bioplex3_WMM WMM_only | |
| TANGO6 | RADX | 0.529 | 0.104 | bioplex_WMM bioplex3_WMM WMM_only | |
| TANGO6 | AHR | 0.523 | 0.12 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| DNAJA1 | AHR | 0.348 | 0.07 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| TANGO6 | DNAJA1 | 0.338 | 0.168 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM boldt_WMM | |
| AHR | RADX | 0.158 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only | |
| PLD2 | SQOR | 0.148 | 0.082 | bioplex3_WMM WMM_only | |
| AHR | SQOR | 0.133 | 0.158 | bioplex3_WMM WMM_only | |
| TANGO6 | SQOR | 0.037 | 0.054 | bioplex3_WMM WMM_only | |
| RADX | SQOR | 0.016 | 0.09 | bioplex3_WMM WMM_only |
Related Complexes