hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01345.1
Complex Portal: CPX-14467
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| XPNPEP3 | Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3) | 5 | UniProt NCBI |
| FGF19 | Fibroblast growth factor 19 (FGF-19) | 5 | UniProt NCBI |
| VIP | VIP peptides [Cleaved into: Intestinal peptide PHV-42 (Peptide histidine valine 42); Intestinal peptide PHM-27 (Peptide histidine methioninamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)] | 5 | UniProt NCBI |
| GDNF | Glial cell line-derived neurotrophic factor (hGDNF) (Astrocyte-derived trophic factor) (ATF) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6832 | 0.0249718442456 | 0.25 | FGF19 | FGF19-FGFR4-KLB complex, heparin induced |
| KEGG:04020 | 0.036316189849 | 0.5 | FGF19 GDNF | Calcium signaling pathway |
| CORUM:6684 | 0.049938562206 | 0.25 | XPNPEP3 | TNFR2 signaling complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| VIP | XPNPEP3 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| XPNPEP3 | GDNF | 0.97 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| XPNPEP3 | FGF19 | 0.956 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes