hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01346.1
Complex Portal: CPX-11929
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CHAF1A | Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150) (hp150) | 5 | UniProt NCBI |
| CHAF1B | Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60) (M-phase phosphoprotein 7) | 5 | UniProt NCBI |
| ATRX | Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf-HX) | 5 | UniProt NCBI |
| CACNA1D | Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Voltage-gated calcium channel subunit alpha Cav1.3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1259 | 1.53774525569e-05 | 0.5 | CHAF1A CHAF1B | Chromatin assembly complex (CAF-1 complex) |
| CORUM:2234 | 1.53774525569e-05 | 0.5 | CHAF1A CHAF1B | Chromatin assembly complex (CAF-1 complex) |
| CORUM:2235 | 5.12488211613e-05 | 0.5 | CHAF1A CHAF1B | ASF1-interacting protein complex |
| CORUM:1149 | 0.000143457417375 | 0.5 | CHAF1A CHAF1B | Histone H3.1 complex |
| HP:0008221 | 0.00454201288615 | 0.5 | CACNA1D ATRX | Adrenal hyperplasia |
| GO:0033186 | 0.00842684400117 | 0.5 | CHAF1A CHAF1B | CAF-1 complex |
| HP:0002717 | 0.018706736024 | 0.5 | CACNA1D ATRX | Adrenal overactivity |
| GO:0006334 | 0.0326725154884 | 0.75 | CHAF1A ATRX CHAF1B | nucleosome assembly |
| GO:0070087 | 0.042122686785 | 0.5 | CHAF1A ATRX | chromo shadow domain binding |
| GO:0006335 | 0.042122686785 | 0.5 | CHAF1A CHAF1B | DNA replication-dependent chromatin assembly |
| CORUM:2233 | 0.049938562206 | 0.25 | CHAF1A | Replication-coupled CAF-1-MBD1-ETDB1 complex |
| CORUM:2839 | 0.049938562206 | 0.25 | ATRX | ATRX-DAXX complex |
| CORUM:2843 | 0.049938562206 | 0.25 | ATRX | ATRX-DAXX complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CHAF1A | CHAF1B | 1.0 | 0.704 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () Malo bioplex3_HCT116 fraction | |
| CHAF1A | ATRX | 0.994 | 0.1 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () | |
| CHAF1B | CACNA1D | 0.991 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CHAF1B | ATRX | 0.972 | 0.046 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| CHAF1A | CACNA1D | 0.455 | bioplex3_WMM WMM_only |
Related Complexes