hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01362.1
Complex Portal: CPX-16358
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2) | 5 | UniProt NCBI |
| SLC35A2 | UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5619072 | 0.0124859221228 | 1.0 | SLC35A2 | Defective SLC35A2 causes congenital disorder of glycosylation 2M (CDG2M) |
| HP:0008695 | 0.0495817777049 | 1.0 | SLC35A2 | Transient nephrotic syndrome |
| HP:0012348 | 0.0495817777049 | 1.0 | SLC35A2 | Decreased galactosylation of N-linked protein glycosylation |
| CORUM:6625 | 0.0499436884912 | 1.0 | SLC35A2 | MGAT4B-SLC35A2(splice variant 1) complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PLCG2 | SLC35A2 | 0.999 | 0.046 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PLCG2 | huMAP3_01362.1 huMAP3_04623.1 huMAP3_06862.1 huMAP3_11991.1 |
| SLC35A2 | huMAP3_01362.1 huMAP3_06172.1 huMAP3_11991.1 |