List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_01365.1

Confidence: Extremely High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
TMOD2	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod)	5	UniProt   NCBI
TFAP2B	Transcription factor AP-2-beta (AP2-beta) (Activating enhancer-binding protein 2-beta)	5	UniProt   NCBI
TFAP2A	Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)	5	UniProt   NCBI
TFAP2C	Transcription factor AP-2 gamma (AP2-gamma) (Activating enhancer-binding protein 2 gamma) (Transcription factor ERF-1)	5	UniProt   NCBI
TFAP2D	Transcription factor AP-2-delta (AP2-delta) (Activating enhancer-binding protein 2-delta) (Transcription factor AP-2-beta-like 1)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-8866904	5.38065562428e-11	0.8	TFAP2B TFAP2D TFAP2A TFAP2C	Negative regulation of activity of TFAP2 (AP-2) family transcription factors
REAC:R-HSA-8866907	8.9672682252e-11	0.8	TFAP2B TFAP2D TFAP2A TFAP2C	Activation of the TFAP2 (AP-2) family of transcription factors
REAC:R-HSA-8864260	1.74513507793e-08	0.8	TFAP2B TFAP2D TFAP2A TFAP2C	Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
REAC:R-HSA-8866910	6.85937538545e-07	0.6	TFAP2B TFAP2A TFAP2C	TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
WP:WP4352	1.26227764043e-05	0.8	TFAP2B TFAP2D TFAP2A TFAP2C	Ciliary landscape
REAC:R-HSA-8866906	9.11829675208e-05	0.4	TFAP2C TFAP2A	TFAP2 (AP-2) family regulates transcription of other transcription factors
REAC:R-HSA-8866911	0.000151950811602	0.4	TFAP2C TFAP2A	TFAP2 (AP-2) family regulates transcription of cell cycle factors
HPA:0410552	0.000365381456275	0.4	TFAP2B TFAP2A	retina; ganglion cells [>=Medium]
HPA:0410551	0.00073847794512	0.4	TFAP2B TFAP2A	retina; ganglion cells [>=Low]
HPA:0411232	0.0011032060519	0.4	TFAP2B TFAP2A	retina; inner nuclear layer[>=Medium]
HPA:0411231	0.00154061066482	0.4	TFAP2B TFAP2A	retina; inner nuclear layer[>=Low]
REAC:R-HSA-3232118	0.001593300657	0.4	TFAP2B TFAP2C	SUMOylation of transcription factors
WP:WP2064	0.015731077008	0.4	TFAP2B TFAP2A	Neural crest differentiation
HPA:0410000	0.0178127213254	0.4	TFAP2B TFAP2A	retina
REAC:R-HSA-212436	0.0184390800992	0.8	TFAP2B TFAP2D TFAP2A TFAP2C	Generic Transcription Pathway
REAC:R-HSA-73857	0.0284318585439	0.8	TFAP2B TFAP2D TFAP2A TFAP2C	RNA Polymerase II Transcription
WP:WP2858	0.0379631029161	0.4	TFAP2C TFAP2A	Ectoderm differentiation
HPA:0461462	0.0444139015161	0.6	TFAP2B TFAP2A TFAP2C	skin 1; langerhans cells[>=Medium]
HPA:0461412	0.0463303695681	0.6	TFAP2B TFAP2A TFAP2C	skin 1; cells in spinous layer[>=Medium]
REAC:R-HSA-74160	0.046583533294	0.8	TFAP2B TFAP2D TFAP2A TFAP2C	Gene expression (Transcription)



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
TFAP2A	TFAP2D	0.999		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116
TMOD2	TFAP2A	0.989	0.076	bioplex3_WMM     bioplex3_HCT116     WMM_only
TFAP2B	TFAP2A	0.988		bioplex3_HEK293     bioplex3_WMM     WMM_only
TFAP2B	TFAP2D	0.977		bioplex3_HEK293     bioplex3_WMM     WMM_only
TFAP2C	TFAP2D	0.973		bioplex3_HEK293     bioplex3_WMM     WMM_only
TMOD2	TFAP2D	0.958		bioplex3_HEK293     bioplex3_WMM     WMM_only
TFAP2A	TFAP2C	0.415	0.12	bioplex3_WMM     WMM_only
TMOD2	TFAP2C	0.102	0.024	bioplex3_WMM     WMM_only





Related Complexes

Genename	Complexes
TMOD2	huMAP3_01365.1 huMAP3_03193.1
TFAP2B	huMAP3_01365.1 huMAP3_02506.1 huMAP3_03193.1 huMAP3_06567.1 huMAP3_07334.1 huMAP3_08604.1 huMAP3_12543.1
TFAP2A	huMAP3_01365.1 huMAP3_03193.1 huMAP3_08604.1
TFAP2C	huMAP3_01365.1 huMAP3_08604.1
TFAP2D	huMAP3_01365.1 huMAP3_03193.1 huMAP3_08604.1