hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
EYA2	Eyes absent homolog 2 (EC 3.1.3.48)	5	UniProt NCBI
EYA3	Eyes absent homolog 3 (EC 3.1.3.48)	5	UniProt NCBI
SIX2	Homeobox protein SIX2 (Sine oculis homeobox homolog 2)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0140789	0.00421361424067	0.666666666667	EYA2 EYA3	histone phosphatase activity
GO:0140793	0.00421361424067	0.666666666667	EYA2 EYA3	histone H2AXY142 phosphatase activity
GO:0007501	0.0140440992017	0.666666666667	EYA2 SIX2	mesodermal cell fate specification
REAC:R-HSA-5693565	0.0168905285744	0.666666666667	EYA2 EYA3	Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
REAC:R-HSA-5693606	0.017372320015	0.666666666667	EYA2 EYA3	DNA Double Strand Break Response
GO:0001710	0.0210651876021	0.666666666667	EYA2 SIX2	mesodermal cell fate commitment
CORUM:7364	0.0499402709677	0.333333333333	SIX2	EYA1-SIX2 complex

Protein 1	Protein 2	Score	ProteomeHD	Evidence
EYA2	SIX2	0.993		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
EYA3	SIX2	0.973	0.054	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
EYA3	EYA2	0.333		bioplex_WMM bioplex3_WMM WMM_only

Genename	Complexes
EYA2	huMAP3_01386.1 huMAP3_05663.1 huMAP3_08067.1 huMAP3_08280.1 huMAP3_09419.1 huMAP3_10131.1 huMAP3_10248.1
EYA3	huMAP3_00067.1 huMAP3_01386.1 huMAP3_05663.1 huMAP3_08067.1 huMAP3_08280.1 huMAP3_08335.1 huMAP3_09419.1 huMAP3_10131.1 huMAP3_10248.1 huMAP3_12159.1
SIX2	huMAP3_01386.1 huMAP3_05663.1 huMAP3_08067.1 huMAP3_08280.1 huMAP3_09419.1 huMAP3_10131.1 huMAP3_10205.1 huMAP3_10248.1