hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01406.1
Complex Portal: CPX-24881
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MUC6 | Mucin-6 (MUC-6) (Gastric mucin-6) | 5 | UniProt NCBI |
| DHH | Desert hedgehog protein (DHH) (EC 3.1.-.-) (HHG-3) [Cleaved into: Desert hedgehog protein N-product (DHH-N)] | 5 | UniProt NCBI |
| RPIA | Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) | 5 | UniProt NCBI |
| PGC | Gastricsin (EC 3.4.23.3) (Pepsinogen C) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2596 | 7.14678770193e-05 | 0.5 | MUC6 PGC | Gastric acid production |
| REAC:R-HSA-5658034 | 0.0499436884912 | 0.25 | DHH | HHAT G278V doesn't palmitoylate Hh-Np |
| REAC:R-HSA-5659996 | 0.0499436884912 | 0.25 | RPIA | RPIA deficiency: failed conversion of R5P to RU5P |
| REAC:R-HSA-6791461 | 0.0499436884912 | 0.25 | RPIA | RPIA deficiency: failed conversion of RU5P to R5P |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MUC6 | DHH | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| DHH | PGC | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| RPIA | DHH | 0.985 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MUC6 | PGC | 0.902 | bioplex3_WMM WMM_only | ||
| RPIA | MUC6 | 0.1 | 0.034 | bioplex3_WMM WMM_only | |
| RPIA | PGC | 0.1 | bioplex3_WMM WMM_only |
Related Complexes