hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
VHL	von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)	5	UniProt NCBI
AVP	Vasopressin-neurophysin 2-copeptin (AVP-NPII) [Cleaved into: Arg-vasopressin (Arginine-vasopressin); Neurophysin 2 (Neurophysin-II); Copeptin]	5	UniProt NCBI
KIRREL2	Kin of IRRE-like protein 2 (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3)	5	UniProt NCBI
OXT	Oxytocin-neurophysin 1 (OT-NPI) [Cleaved into: Oxytocin (Ocytocin); Neurophysin 1]	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
HPA:0260133	2.61273645901e-05	0.5	AVP OXT	hypothalamus; neuronal cells[High]
REAC:R-HSA-388479	3.07549051138e-05	0.5	AVP OXT	Vasopressin-like receptors
HPA:0260132	0.000156692671033	0.5	AVP OXT	hypothalamus; neuronal cells[>=Medium]
HPA:0260131	0.000287191244891	0.5	AVP OXT	hypothalamus; neuronal cells[>=Low]
HPA:0260142	0.000339376853931	0.5	AVP OXT	hypothalamus; neuronal projections[>=Medium]
HPA:0260141	0.000395903520345	0.5	AVP OXT	hypothalamus; neuronal projections[>=Low]
HPA:0260000	0.000591517957266	0.5	AVP OXT	hypothalamus
GO:0031893	0.0028092043205	0.5	AVP OXT	vasopressin receptor binding
GO:0031894	0.0028092043205	0.5	AVP OXT	V1A vasopressin receptor binding
KEGG:04080	0.0428875882852	0.5	AVP OXT	Neuroactive ligand-receptor interaction
REAC:R-HSA-375276	0.046351696636	0.5	AVP OXT	Peptide ligand-binding receptors
REAC:R-HSA-9036092	0.0499436884912	0.25	AVP	Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI)

Protein 1	Protein 2	Score	Evidence
VHL	OXT	0.984	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
VHL	KIRREL2	0.981	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
VHL	AVP	0.98	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM

Genename	Complexes
VHL	huMAP3_01414.1 huMAP3_08992.1 huMAP3_12200.1 huMAP3_15324.1
AVP	huMAP3_01414.1 huMAP3_12866.1
KIRREL2	huMAP3_01414.1 huMAP3_03806.1 huMAP3_08992.1 huMAP3_13639.1
OXT	huMAP3_01414.1 huMAP3_04269.1 huMAP3_08992.1 huMAP3_13381.1 huMAP3_14611.1 huMAP3_14845.1 huMAP3_15324.1