hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01425.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MMP14 | Matrix metalloproteinase-14 (MMP-14) (EC 3.4.24.80) (MMP-X1) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) | 5 | UniProt NCBI |
| ALG2 | Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-4549349 | 0.0249718442457 | 0.5 | ALG2 | Defective ALG2 causes CDG-1i |
| CORUM:2688 | 0.0249718442457 | 0.5 | MMP14 | MMP14-CLDN1 complex |
| HP:0000612 | 0.0440177027348 | 1.0 | ALG2 MMP14 | Iris coloboma |
| CORUM:6193 | 0.0499419797295 | 0.5 | MMP14 | ADAM12-alphaVbeta3-integrin-MMP-14 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MMP14 | ALG2 | 0.977 | 0.052 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| MMP14 | huMAP3_01425.1 huMAP3_11949.1 huMAP3_12426.1 |
| ALG2 | huMAP3_01425.1 huMAP3_11567.1 huMAP3_11708.1 |