hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01438.1
Complex Portal: CPX-20708
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ALS2CL | ALS2 C-terminal-like protein | 5 | UniProt NCBI |
| ALS2 | Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8876198 | 0.0055363880769 | 1.0 | ALS2CL ALS2 | RAB GEFs exchange GTP for GDP on RABs |
| REAC:R-HSA-9007101 | 0.0098732254038 | 1.0 | ALS2CL ALS2 | Rab regulation of trafficking |
| HP:0002501 | 0.0499436884913 | 0.5 | ALS2 | Spasticity of pharyngeal muscles |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ALS2CL | ALS2 | 0.977 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| ALS2CL | huMAP3_01438.1 huMAP3_12005.1 |
| ALS2 | huMAP3_01438.1 huMAP3_12005.1 |