hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_01440.1

Complex Portal: CPX-14140

Confidence: Extremely High

Genename	Protein Name	Uniprot Annotation Score	Links
H4C1	Histone H4	5	UniProt NCBI
H3-3A	Histone H3.3	5	UniProt NCBI
CHAF1A	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150) (hp150)	5	UniProt NCBI
NASP	Nuclear autoantigenic sperm protein (NASP)	5	UniProt NCBI
HAT1	Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48) (Histone acetyltransferase 1)	5	UniProt NCBI
NPAT	Protein NPAT (Nuclear protein of the ataxia telangiectasia mutated locus) (Nuclear protein of the ATM locus) (p220)	5	UniProt NCBI
H3-7	Histone H3-7	4	UniProt NCBI
ATRX	Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf-HX)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:1149	2.61731336666e-07	0.5	NASP CHAF1A HAT1	Histone H3.1 complex
CORUM:1150	0.000358512652571	0.333333333333	NASP HAT1	Histone H3.3 complex
GO:0006334	0.000651135687142	0.666666666667	NASP ATRX CHAF1A HAT1	nucleosome assembly
GO:0034728	0.00141109188279	0.666666666667	NASP ATRX CHAF1A HAT1	nucleosome organization
HPA:0600433	0.00147463021626	0.833333333333	NASP H3-7 ATRX CHAF1A HAT1	tonsil; germinal center cells[High]
HPA:0460182	0.00225214430703	0.666666666667	NASP ATRX HAT1 H3-7	skin 1; cells in granular layer[>=Medium]
HPA:0470182	0.00226924641445	0.666666666667	NASP ATRX HAT1 H3-7	skin 2; cells in granular layer[>=Medium]
HPA:0461462	0.00284889960473	0.666666666667	NASP ATRX HAT1 H3-7	skin 1; langerhans cells[>=Medium]
HPA:0461412	0.00301480157617	0.666666666667	NASP ATRX HAT1 H3-7	skin 1; cells in spinous layer[>=Medium]
HPA:0461392	0.00408513148247	0.666666666667	NASP ATRX HAT1 H3-7	skin 1; cells in basal layer[>=Medium]
HPA:0471462	0.0045836454994	0.666666666667	NASP ATRX HAT1 H3-7	skin 2; langerhans cells[>=Medium]
HPA:0471412	0.00509454954532	0.666666666667	NASP ATRX HAT1 H3-7	skin 2; cells in spinous layer[>=Medium]
HPA:0460181	0.00595593387728	0.666666666667	NASP ATRX HAT1 H3-7	skin 1; cells in granular layer[>=Low]
HPA:0470181	0.00602637789862	0.666666666667	NASP ATRX HAT1 H3-7	skin 2; cells in granular layer[>=Low]
HPA:0461461	0.00657454067564	0.666666666667	NASP ATRX HAT1 H3-7	skin 1; langerhans cells[>=Low]
HPA:0471392	0.00773783800644	0.666666666667	NASP ATRX HAT1 H3-7	skin 2; cells in basal layer[>=Medium]
HPA:0471413	0.00802673874285	0.5	NASP HAT1 H3-7	skin 2; cells in spinous layer[High]
HPA:0461411	0.00826115629436	0.666666666667	NASP ATRX HAT1 H3-7	skin 1; cells in spinous layer[>=Low]
HPA:0471461	0.00909458866193	0.666666666667	NASP ATRX HAT1 H3-7	skin 2; langerhans cells[>=Low]
HPA:0471463	0.00974819125554	0.5	NASP HAT1 H3-7	skin 2; langerhans cells[High]
HPA:0471442	0.0110562277767	0.666666666667	NASP ATRX HAT1 H3-7	skin 2; fibrohistiocytic cells[>=Medium]
GO:0065004	0.0112661365493	0.666666666667	NASP ATRX CHAF1A HAT1	protein-DNA complex assembly
HPA:0460201	0.0116205574152	0.666666666667	NASP ATRX HAT1 H3-7	skin 1; endothelial cells[>=Low]
HPA:0471411	0.0134414004631	0.666666666667	NASP ATRX HAT1 H3-7	skin 2; cells in spinous layer[>=Low]
HPA:0470201	0.0142924432647	0.666666666667	NASP ATRX HAT1 H3-7	skin 2; endothelial cells[>=Low]
HPA:0461391	0.0144268140259	0.666666666667	NASP ATRX HAT1 H3-7	skin 1; cells in basal layer[>=Low]
HPA:0470203	0.0163244503815	0.5	NASP ATRX H3-7	skin 2; endothelial cells[High]
HPA:0471391	0.0200007903901	0.666666666667	NASP ATRX HAT1 H3-7	skin 2; cells in basal layer[>=Low]
HPA:0471441	0.0244392450348	0.666666666667	NASP ATRX HAT1 H3-7	skin 2; fibrohistiocytic cells[>=Low]
HPA:0461473	0.029812902218	0.5	H3-7 HAT1 ATRX	skin 1; lymphocytes[High]

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
H4C1	HAT1	0.998	0.347671230091	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM
H4C1	NASP	0.997		structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM
CHAF1A	H4C1	0.996	0.271650649666		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
CHAF1A	ATRX	0.994	0.1		hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein ()
ATRX	H4C1	0.993	0.490862888483		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
H4C1	H3-3A	0.988	0.946	mutually_exclusive (Q5TEC6)	bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM treiber_WMM WMM_only
NASP	HAT1	0.984		structurally_consistent (dimer)	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction treiber_WMM
H3-3A	NASP	0.984			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM
H4C1	NPAT	0.982	0.612		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
HAT1	NPAT	0.969	0.158		bioplex_WMM bioplex3_WMM youn_WMM WMM_only
ATRX	H3-3A	0.962	0.37697029703		bioplex3_HEK293 bioplex3_WMM youn_WMM WMM_only
CHAF1A	NASP	0.949			bioplex_WMM bioplex3_WMM youn_WMM fraction
H3-3A	HAT1	0.841	0.261168408827		bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only
NASP	NPAT	0.832			bioplex_WMM bioplex3_WMM youn_WMM WMM_only
CHAF1A	HAT1	0.75	0.138	mutually_exclusive (Q09028)	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
CHAF1A	NPAT	0.728	0.12		bioplex_WMM bioplex3_WMM youn_WMM WMM_only
ATRX	NPAT	0.596	0.136		bioplex_WMM bioplex3_WMM youn_WMM WMM_only
H3-3A	NPAT	0.293	0.53073458445		hein_WMM bioplex3_WMM youn_WMM WMM_only
ATRX	NASP	0.157			bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
CHAF1A	H3-3A	0.14	0.312086148649	structurally_consistent (dimer)	bioplex3_HEK293 bioplex3_WMM WMM_only
ATRX	HAT1	0.051	0.1		bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only

Related Complexes

Genename	Complexes
H4C1	huMAP3_01440.1 huMAP3_05517.1 huMAP3_05966.1 huMAP3_06020.1 huMAP3_07824.1 huMAP3_08143.1 huMAP3_09048.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_10862.1 huMAP3_12711.1
H3-3A	huMAP3_01440.1 huMAP3_05966.1 huMAP3_08143.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_12711.1
CHAF1A	huMAP3_01346.1 huMAP3_01440.1 huMAP3_05517.1 huMAP3_05966.1 huMAP3_06469.1 huMAP3_08513.1 huMAP3_09859.1 huMAP3_10512.1 huMAP3_10747.1 huMAP3_11491.1 huMAP3_11539.1 huMAP3_11834.1 huMAP3_12711.1
NASP	huMAP3_01440.1 huMAP3_05517.1 huMAP3_05966.1 huMAP3_06020.1 huMAP3_08143.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_12711.1 huMAP3_12925.1
HAT1	huMAP3_01440.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_07299.1 huMAP3_08143.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_12711.1 huMAP3_13482.1 huMAP3_15128.1
NPAT	huMAP3_01440.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_07299.1 huMAP3_08143.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_12711.1 huMAP3_15128.1
H3-7	huMAP3_01440.1 huMAP3_04941.1 huMAP3_05966.1 huMAP3_07969.1 huMAP3_08143.1 huMAP3_09048.1 huMAP3_09387.1 huMAP3_09859.1 huMAP3_10592.1 huMAP3_10747.1 huMAP3_10862.1
ATRX	huMAP3_01346.1 huMAP3_01440.1 huMAP3_05966.1 huMAP3_06469.1 huMAP3_08143.1 huMAP3_09859.1 huMAP3_10512.1 huMAP3_10747.1 huMAP3_11539.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_01440.1

Complex Portal: CPX-14140